Protein Alignment CrzR and SIFaR

DIOPT Version :9

• Sequence 1: NP_001261755.1
• Gene: CrzR / 39409
• FlyBaseID: FBgn0036278
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001163674.1
• Gene: SIFaR / 42530
• FlyBaseID: FBgn0038880
• Length: 758
• Species: Drosophila melanogaster
• Alignment Length: 611
• Identity: 131/611 - (21%)
• Similarity: 237/611 - (38%)
• Gaps: 130/611 - (21%)

  Fly    15 PSASMDLET--ENEVVSNWSTLANFTRLVAGAAPEIVNYTLNMIDVGVGMATDISNLSVSTTPLP 77
            |:||..|.|  .....|...:||..:..:|.|...  .|..|::           |||.:||.|
  Fly   119 PAASSLLATLAATTTASARGSLAGKSLAIADATSS--TYYSNLL-----------NLSPATTSL- 169

  Fly    78 AYAISNSSSLAHTNSRHEAPPMAEQVPEHVMDHAPQLSRSGLL--KVYVLAVMALF--SLLGNLL 138
                  .|:.|.|.|.:::....||:...|......|.|..|.  .||.:|.:.:|  .|:||..
  Fly   170 ------ISAAAATKSYNDSALRWEQLDGSVDFGFDPLYRHSLAMSMVYCVAYIVVFLVGLIGNSF 228

  Fly   139 TIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYTVQWLANELTCKLVKL 203
            .|..:.:....|..:.:       .:.:|:|||:||..||:.........|.|:...|.||.|..
  Fly   229 VIAVVLRAPRMRTVTNY-------FIVNLAIADILVIVFCLPATLIGNIFVPWMLGWLMCKFVPY 286

  Fly   204 FQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCHRLLGGTYILSLVLSLPQFFIFHVARGP 268
            .|..|:..|.|.|:.:.:||:||:.:|:|.:. .:|...::.|.::::||.::|....|.:.  |
  Fly   287 IQGVSVAASVYSLIAVSLDRFIAIWWPLKQMT-KRRARIMIIGIWVIALVTTIPWLLFFDLV--P 348

  Fly   269 FVEEFYQCVTHGFYTADWQEQ-----------MYATFTLVFTFLLPLCILFGTYMSTFRTISSSE 322
            ..|.|...:...:....:..|           .:....||..:|||:.::...|:..:..:
  Fly   349 AEEVFSDALVSAYSQPQFLCQEVWPPGTDGNLYFLLANLVACYLLPMSLITLCYVLIWIKV---- 409

  Fly   323 KMFQGSKLANYSTAKLPTQT---NRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMMIMFMFLN 384
                       ||..:|.::   ...|:..|:|:|.:::.|.::|.|::.|.|.||:.....|
  Fly   410 -----------STRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKF-- 461

  Fly   385 PDKRLGDDLQDAIF-----------FFGMSNSLVNPLIYGAFHLCPGKGGKSSGGGGNNNAYSLN 438
                 |.|:....|           :.|.|||.:||::|..                 |..|...
  Fly   462 -----GSDISQEEFEILKKVMPVAQWLGSSNSCINPILYSV-----------------NKKYRRG 504

  Fly   439 RGDSQRTPSMLTAVTQVDGTGGSSRQMRAFRQQSYYRSSSNGTAGPGAAPFKEQVGLLHVGPGNG 503
            .....::.|....:...|....:|......:...|:::||.      .:|..:...:.::...|.
  Fly   505 FAAIIKSRSCCGRLRYYDNVAIASSTTSTRKSSHYHQNSSR------KSPSSKGNAVSYIYEHNS 563

  Fly   504 TPGGSV-----------------SSGATPQLIRKGS----ALLARQPSCLREQEHQQRLLLHEKP 547
            ....::                 |.|:...||::.|    |...|:|.| ::..:..::.|.::.
  Fly   564 LRRHNMMLKQDSNLSQQMLLKQDSHGSRQFLIKQESSCSDASGIRRPLC-QQDSNGSKVSLSKQD 627

  Fly   548 STLVLSYDSQRGGVGVGVASGLLDNN 573
            |  ::||...|...|.|:...|:|.:
  Fly   628 S--IVSYMEARRSAGHGLNDTLVDRD 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	36/134 (27%)
		7tm_1	135..412	CDD:278431	69/301 (23%)
SIFaR	NP_001163674.1	7tm_4	216..>443	CDD:304433	55/251 (22%)
		7tm_1	225..495	CDD:278431	69/301 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472990
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840