Protein Alignment CrzR and RXFP4

DIOPT Version :9

• Sequence 1: NP_001261755.1
• Gene: CrzR / 39409
• FlyBaseID: FBgn0036278
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_871001.1
• Gene: RXFP4 / 339403
• HGNCID: 14666
• Length: 374
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 92/438 - (21%)
• Similarity: 160/438 - (36%)
• Gaps: 113/438 - (25%)

  Fly    69 LSVSTTPLPAYAISNSSSLAHTNSRHEAPPMAEQVPEHVMDHAPQLSRSGLLKVYVLAVMAL--- 130
            |:.|.:| |.:..:|:|..:..::                |.||...:...|::.|.....|
Human     4 LNTSASP-PTFFWANASGGSVLSA----------------DDAPMPVKFLALRLMVALAYGLVGA 51

  Fly   131 FSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADV-----LVTWFCIIGEAAWCYTVQ 190
            ..|||||..:|     .:|....|.......:.:|:|::||:     |..|   ..|:|..:  .
Human    52 IGLLGNLAVLW-----VLSNCARRAPGPPSDTFVFNLALADLGLALTLPFW---AAESALDF--H 106

  Fly   191 WLANELTCKLVKLFQMFSLYLSTYVLVLIGVDR-WIAVKYPMKSLNMAKRCHRLLGGTYILSLVL 254
            |......||:|....:.::|.|.:::..:.|.| |:.      ::......|..|....|.:|.:
Human   107 WPFGGALCKMVLTATVLNVYASIFLITALSVARYWVV------AMAAGPGTHLSLFWARIATLAV 165

  Fly   255 SLPQFFIFHVARGPFVEEFYQCVTH----GFYTADWQEQMYATFTLVFTFLLPLCILFGTYMSTF 315
            ......: .|....|..|...|...    .|.:..|. ..|....:|..|::||.::..:|:...
Human   166 WAAAALV-TVPTAVFGVEGEVCGVRLCLLRFPSRYWL-GAYQLQRVVLAFMVPLGVITTSYLLLL 228

  Fly   316 RTISSSEKMFQGSKLANYSTAKLPTQTNRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMM--- 377
            ..:...::..|.|::.                     .:|:||   ::.:|.:||.|.:|:.
Human   229 AFLQRRQRRRQDSRVV---------------------ARSVRI---LVASFFLCWFPNHVVTLWG 269

  Fly   378 IMFMF-LNPDKRLGDDLQDAIF----FFGMSNSLVNPLIY------------GAF-----HLCPG 420
            ::..| |.|.......:|..:|    ....|||.:||::|            |.|     .|.|.
Human   270 VLVKFDLVPWNSTFYTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQ 334

  Fly   421 KGG-------KSSGGGGNNNAYSLNRGDSQRTPSMLTAVTQVD-GTGG 460
            .||       |..|    ....:.|..:|:  ||  |.:|.:| ||.|
Human   335 GGGWVQQVALKQVG----RRWVASNPRESR--PS--TLLTNLDRGTPG 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	30/141 (21%)
		7tm_1	135..412	CDD:278431	59/294 (20%)
RXFP4	NP_871001.1	7tm_1	56..309	CDD:278431	59/294 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100