DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CrzR and CCKLR-17D3

DIOPT Version :9

Sequence 1:	NP_001261755.1	Gene:	CrzR / 39409	FlyBaseID:	FBgn0036278	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001097023.1	Gene:	CCKLR-17D3 / 32864	FlyBaseID:	FBgn0030954	Length:	584	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	117/548 - (21%)
Similarity:	183/548 - (33%)	Gaps:	207/548 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 MATDISNLSVSTTPLPAYAISNSSSLAHTNSRHEAPPMAEQVPEHVMDHAPQLSRSGLLKVYVL- 125
            |.|:.|:|   .|.| |:::..|||           |.....|      |...|.|..:.|:::
  Fly    73 MDTEPSDL---VTEL-AFSLGTSSS-----------PSPSSTP------ASSSSTSTGMPVWLIP 116

  Fly   126 --AVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYT 188
              :::.||::|||||.|    .|.:..|..| |.:.::  :.:|:|:|:|:...|:.........
  Fly   117 SYSMILLFAVLGNLLVI----STLVQNRRMR-TITNVF--LLNLAISDMLLGVLCMPVTLVGTLL 174

  Fly   189 VQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCHRL-------LGG 246
            ..::..|..|||.:..|..|:.:|::.||.|..:|:.|:.:|::|.:.....|..       |||
  Fly   175 RNFIFGEFLCKLFQFSQAASVAVSSWTLVAISCERYYAICHPLRSRSWQTISHAYKIIGFIWLGG 239

  Fly   247 TYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTADWQEQMYATF-TLVFTFL---LPLCIL 307
            ...::.:....|..       |.....| |....|    |.:|.|..| .::..||   |||.:|
  Fly   240 ILCMTPIAVFSQLI-------PTSRPGY-CKCREF----WPDQGYELFYNILLDFLLLVLPLLVL 292

  Fly   308 FGTYMSTFRTI--------------------------------SSSEKMF--------------- 325
            ...|:...||:                                |||....
  Fly   293 CVAYILITRTLYVGMAKDSGRILQQSLPVSATTAGGSAPNPGTSSSSNCILVLTATAVYNENSNN 357

  Fly   326 --------QGSKLANYSTAKLPTQTNRQRLI--------------------HKA----------- 351
                    .|....|.:|..|.|:.....:|                    |.|
  Fly   358 NNGNSEGSAGGGSTNMATTTLTTRPTAPTVITTTTTTTVTLAKTSSPSIRVHDAALRRSNEAKTL 422

  Fly   352 --KMKSLRISVVIIIAFLICWTPYYVMMIMFMFLNP------DKRLGDDLQDAIFFFGM---SNS 405
              |.:.:::..|:::.|.|||||.||:..|.|.:.|      |       ..||.|..:   |:|
  Fly   423 ESKKRVVKMLFVLVLEFFICWTPLYVINTMVMLIGPVVYEYVD-------YTAISFLQLLAYSSS 480

  Fly   406 LVNPLIY------------GAFHLCPGKGGKSSGGGGNNNAYSLNRGDSQRTPSMLTAVTQVDGT 458
            ..||:.|            ..|...|.:.|..:.||                         |.|.
  Fly   481 CCNPITYCFMNASFRRAFVDTFKGLPWRRGAGASGG-------------------------VGGA 520

  Fly   459 GGSSRQMRAFRQQSYYRSSSNGTAGPGA 486
            .|..            .|:|...|||||
  Fly   521 AGGG------------LSASQAGAGPGA 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	36/139 (26%)
CrzR	NP_001261755.1	7tm_1	135..412	CDD:278431	82/384 (21%)
CCKLR-17D3	NP_001097023.1	7tm_4	120..>244	CDD:304433	35/130 (27%)
CCKLR-17D3	NP_001097023.1	7tm_1	128..487	CDD:278431	82/384 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472994
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840