DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CrzR and Galr2

DIOPT Version :9

Sequence 1:	NP_001261755.1	Gene:	CrzR / 39409	FlyBaseID:	FBgn0036278	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_062045.1	Gene:	Galr2 / 29234	RGDID:	2657	Length:	372	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	88/380 - (23%)
Similarity:	159/380 - (41%)	Gaps:	67/380 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 DHAPQLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVL 173
            ::..|...||..:...:.|...|:|:..:.|:.|.....:..|..:.. |.....:.:|.:||:.
  Rat    10 ENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAV-STTNLFILNLGVADLC 73

  Fly   174 VTWFCIIGEAAWCYTV-QWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKS--LN 235
            ....|:..:|. .||: .|:...|.||.|......:::.|::.|..:.:||::|::||:.|  |.
  Rat    74 FILCCVPFQAT-IYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELR 137

  Fly   236 MAKRCHRLLGGTYILSLVLSLPQFFIFHVARGPFVEEFYQ------CVTHGFYTADWQEQMYATF 294
            ..:.....:|..:.|:|:.|           ||::..:.|      .|.|..::|..:..| ...
  Rat   138 TPRNALAAIGLIWGLALLFS-----------GPYLSYYRQSQLANLTVCHPAWSAPRRRAM-DLC 190

  Fly   295 TLVFTFLLPLCILFGTYMSTFRTI-SSSEKMFQGSKLANYSTAKLPTQTNRQRLIHKAKMKSLRI 358
            |.||::|||:.:|..||..|.|.: .:.:.:..||              ..||    ||.|..|:
  Rat   191 TFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGS--------------GSQR----AKRKVTRM 237

  Fly   359 SVVIIIAFLICWTPYYVMMIMFMFLN-PDKRLGDDLQDAIFFFGMSNSLVNPLIY---------G 413
            .:::.:.|.:||.|::.:::...|.. |..|....|:........:||.|||::|         |
  Rat   238 IIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKG 302

  Fly   414 AFHLCPG--------KGGKSSGGGGNNNAYSLNRGDSQRTPSMLTAVTQVDGTGG 460
            ...:|.|        ..|:.|.....|::.|:...:|       |.:|||....|
  Rat   303 FRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQES-------TDLTQVSEAAG 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	32/135 (24%)
CrzR	NP_001261755.1	7tm_1	135..412	CDD:278431	68/287 (24%)
Galr2	NP_062045.1	7tm_4	32..>177	CDD:304433	35/157 (22%)
		7tm_1	42..292	CDD:278431	67/281 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	353..372
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010