Protein Alignment CrzR and GALR1

DIOPT Version :9

• Sequence 1: NP_001261755.1
• Gene: CrzR / 39409
• FlyBaseID: FBgn0036278
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001471.2
• Gene: GALR1 / 2587
• HGNCID: 4132
• Length: 349
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 89/356 - (25%)
• Similarity: 143/356 - (40%)
• Gaps: 79/356 - (22%)

  Fly    80 AISNSSSLAHTNSRHEAPPMAEQVPEHVMDHAPQLSRSGLLKVYVLAVMAL-FSL--LGNLLTIW 141
            |:.|   |:..|:....||..|..|         |...|:.....|.|..| |:|  |||.|.|
Human     4 AVGN---LSEGNASWPEPPAPEPGP---------LFGIGVENFVTLVVFGLIFALGVLGNSLVI- 55

  Fly   142 NIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYTVQWLANELTCKLVKLFQM 206
                |.::|.......|.....:.:|||||:....|||..:|.......|:.....||.:..|..
Human    56 ----TVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFT 116

  Fly   207 FSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCHRLL--GGTYILSLVLSLPQFF---IFHVAR 266
            .|:.:|.:.|..:.|||::|:.:..:|.::....:.||  |..:.||:.::.|..:   :||.
Human   117 VSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHP-- 179

  Fly   267 GPFVEEFYQCVTHGFYTADW----QEQMYATFTLVFTFLLPLCILFGTYMSTFRTISSSEKMFQG 327
                    :.....|....|    .::.|...|.||.:||||.::...|
Human   180 --------RASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCY---------------- 220

  Fly   328 SKLANYSTAKLPTQTNRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMMIMFMF----LNPDKR 388
            :|:.|:...||   .|..:....:|.|:.:..:|:::.|.|.|.|::::.:...|    |.|
Human   221 AKVLNHLHKKL---KNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTP--- 279

  Fly   389 LGDDLQDAIFFF-------GMSNSLVNPLIY 412
                   |.|.|       ..|||.|||:||
Human   280 -------ASFLFRITAHCLAYSNSSVNPIIY 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	39/137 (28%)
		7tm_1	135..412	CDD:278431	71/296 (24%)
GALR1	NP_001471.2	7tm_1	50..303	CDD:278431	71/296 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010