Protein Alignment CrzR and gnrr-4

DIOPT Version :9

• Sequence 1: NP_001261755.1
• Gene: CrzR / 39409
• FlyBaseID: FBgn0036278
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_741799.1
• Gene: gnrr-4 / 180841
• WormBaseID: WBGene00016570
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 506
• Identity: 108/506 - (21%)
• Similarity: 190/506 - (37%)
• Gaps: 120/506 - (23%)

  Fly   113 QLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSA--IYSLMFHLSIADVLVT 175
            :||.|..|::::..:.....|...:.|:..:.::|.||   :|...|  ::|....||:||.:|.
 Worm    13 ELSFSYTLELWMYGIAFCVGLPAFIFTVVRLARSRSSR---QHLVLAARLFSYKISLSVADCIVL 74

  Fly   176 WFCIIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDR-WIAVKYPMKSLNMAKR 239
            :.....:.||.::..|...::.|:|.|....|..:|:..:.||:..|| .|..|....:.|:.||
 Worm    75 FIYAPTQFAWIHSYWWFGGDIGCRLFKFISTFGFHLTANMQVLVAADRLLITAKMNRVTRNIKKR 139

  Fly   240 CH--RL-LGGTYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTADWQE---QMYATFTLVF 298
            .:  || |...:||:|:.:.||..:|.....|  :.:.||:      :.|.|   ..|....|:.
 Worm   140 QYNTRLSLAAAWILALICAGPQLILFRQKTTP--QGYPQCI------SIWTEHRVDFYDRLELLE 196

  Fly   299 TFLLPLCILFGTYMSTFRTISSSEKMFQGSKLANYSTAKLPTQ---------TNRQRLIHKAKMK 354
            .:         .||.......|....|:...| .|:....|::         ||.:..::..::.
 Worm   197 QY---------AYMQHELANKSPIYFFENGTL-RYAKEDFPSEPGFTLEELHTNNRNWLYLERLY 251

  Fly   355 S-LRISVVIIIAF---LICWTPYYVMMIMFMFLNPDK----RLGDDLQDAIFFFGMSNSLVNPLI 411
            : |.::.:.:|.:   |||:|     :|:::.....|    .|.|.::| ||
 Worm   252 NVLHLATICVIPYAMELICYT-----LILYILKGASKGRFVSLSDIVKD-IF------------- 297

  Fly   412 YGAFHLCPGKGGKSSGGGGNNNAYSLNRGDSQRTPSMLTAVTQVDGTGGSSRQMRAFRQQS---- 472
                  |..|..:.......:|....:.....|.||....:..: ...|.|..|...|..|
 Worm   298 ------CCCKRARQHESPIESNVTQESDNLMARVPSKTKRLQNI-APEGKSCDMERRRAASVDVP 355

  Fly   473 --YYRSSS-------NGTAGPGAAP---------------FKEQV-----GLLHVGPGNGTPGGS 508
              ...|||       ||:|.....|               ||.:|     .|.|    ||:.|..
 Worm   356 MRIKNSSSLTVCIDENGSATAATRPEVTPQEQEPETRTQAFKRRVWNFLLDLFH----NGSEGSV 416

  Fly   509 VSSGATPQLIRKGSALLARQPSCLREQEHQQRLLLHEKPSTL-VLSYDSQR 558
            ..:|...:|         |.|:..:.:..:|......:.:|| |::.|:.|
 Worm   417 HFNGHKTEL---------RLPNLTKGEARRQSAPASARSNTLWVVTVDTAR 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	38/138 (28%)
		7tm_1	135..412	CDD:278431	67/302 (22%)
gnrr-4	NP_741799.1	7tm_GPCRs	25..>179	CDD:391938	42/164 (26%)
		TM helix 1	25..46	CDD:341315	2/20 (10%)
		TM helix 2	59..86	CDD:341315	8/26 (31%)
		TM helix 3	97..126	CDD:341315	9/28 (32%)
		TM helix 4	139..163	CDD:341315	9/23 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368588at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920