DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CrzR and Galr3

DIOPT Version :9

Sequence 1:	NP_001261755.1	Gene:	CrzR / 39409	FlyBaseID:	FBgn0036278	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_056553.2	Gene:	Galr3 / 14429	MGIID:	1329003	Length:	370	Species:	Mus musculus

Alignment Length:	307	Identity:	68/307 - (22%)
Similarity:	128/307 - (41%)	Gaps:	56/307 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 VLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYT 188
            |.|::.|..::||.|.:..:.:...|......:.:.::.|  :|::||:.....|:..:|| .||
Mouse    23 VFALIFLLGMVGNGLVLAVLLQPGPSAWQEPGSTTDLFIL--NLAVADLCFILCCVPFQAA-IYT 84

  Fly   189 VQ-WLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKS--LNMAKRCHRLLGGTYIL 250
            :. ||.....||.|.|....::|.|::.|..:.|||::||::|::|  |...:.....:|..::|
Mouse    85 LDAWLFGAFVCKTVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLL 149

  Fly   251 SLVLSLPQFFIFHVARGPFVEEFYQCVTHG---FYTADWQEQM-----YATFTLVFTFLLPLCIL 307
            :.:.|.|..            .:|..|.:|   .....|::..     .|||..  .:|||:.::
Mouse   150 AALFSAPYL------------SYYGTVRYGALELCVPAWEDARRRALDVATFAA--GYLLPVTVV 200

  Fly   308 FGTYMSTFRTISSSEKMFQGSKLANYSTAKLPTQTNRQRLIHKAKMKSLRISVVIIIAFLICWTP 372
            ...|               |..|.....|..|..........:|..::.|..:.:...:.:||.|
Mouse   201 SLAY---------------GRTLCFLWAAVGPAGAAAAEARRRATGRAGRAMLTVAALYALCWGP 250

  Fly   373 YYVMMIMFMF----LNPDK---RLGDDLQDAIFFFGMSNSLVNPLIY 412
            ::.:::.|.:    .:|..   ||      |......:||.:|||:|
Mouse   251 HHALILCFWYGRFAFSPATYACRL------ASHCLAYANSCLNPLVY 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	35/135 (26%)
CrzR	NP_001261755.1	7tm_1	135..412	CDD:278431	64/294 (22%)
Galr3	NP_056553.2	7tm_4	24..>162	CDD:304433	36/152 (24%)
		7tm_1	34..291	CDD:278431	64/294 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100