Protein Alignment CrzR and mchr2

DIOPT Version :9

• Sequence 1: NP_001261755.1
• Gene: CrzR / 39409
• FlyBaseID: FBgn0036278
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001297035.1
• Gene: mchr2 / 100490064
• XenbaseID: XB-GENE-981280
• Length: 342
• Species: Xenopus tropicalis
• Alignment Length: 327
• Identity: 64/327 - (19%)
• Similarity: 139/327 - (42%)
• Gaps: 67/327 - (20%)

  Fly   106 HVMDHAPQLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIA 170
            |:.|.|..:    :|..:: .::....|:||:|.:..|.::|      |.|...||  :.:|::|
 Frog    27 HITDTAETV----ILPSFI-GIICSTGLVGNILVLITIIRSR------RKTIPDIY--ICNLAVA 78

  Fly   171 DVLVTWFCIIGEA----AWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYP- 230
            |::    .|||..    .|....:|:.....|.::......:.:..|.::..:.:||::|:..|
 Frog    79 DLV----HIIGMPFLIHQWARGGEWVFGSPLCTIITSLDTCNQFACTAIMTAMSLDRYMALVQPF 139

  Fly   231 ----MKSLNMAKRCHRLLGGTYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTAD--WQEQ 289
                :::::...|.:.||   :..|.::..|.:....|.:  |.:....|........|  |
 Frog   140 RLTSLRTISKTIRVNVLL---WAASFIVVFPVWVYSKVIQ--FKDGLESCAFDLTTPNDVLW--- 196

  Fly   290 MYATFTLVFTFLLPLCILFGTYMSTFRTISSSEKMFQGSKLANYSTAKLPTQTNRQRLIHKAKMK 354
             |..:..:.||..||.::...|:   ..:..:.:|:..:|.|......:|    |||::...||
 Frog   197 -YTLYLTITTFFFPLPLILACYI---LILCYTWEMYHQNKSAGRYNNSIP----RQRVLRLTKM- 252

  Fly   355 SLRISVVIIIAFLICWTPYYVMMIMFMFLNPDKRLGDDLQDAIFFF---------GMSNSLVNPL 410
                .:|::..:::...||:|:.|:.:.::         |.::.|:         ..::|.:||.
 Frog   253 ----VLVLVGVYIVSSAPYHVIQIVNLQIS---------QPSLTFYVSYYCSICLSYASSGINPF 304

  Fly   411 IY 412
            :|
 Frog   305 LY 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tm_4	127..>260	CDD:304433	29/141 (21%)
		7tm_1	135..412	CDD:278431	58/296 (20%)
mchr2	NP_001297035.1	7tmA_MCHR2	35..317	CDD:320461	61/319 (19%)
		TM helix 1	36..62	CDD:320461	6/26 (23%)
		TM helix 2	68..94	CDD:320461	8/31 (26%)
		TM helix 3	106..136	CDD:320461	5/29 (17%)
		TM helix 4	148..168	CDD:320461	4/22 (18%)
		TM helix 5	194..223	CDD:320461	7/35 (20%)
		TM helix 6	244..274	CDD:320461	9/34 (26%)
		TM helix 7	285..310	CDD:320461	4/22 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010