Protein Alignment CrzR and gnrhr2/nmi

DIOPT Version :10

• Sequence 1: NP_001261755.1
• Gene: CrzR / 39409
• FlyBaseID: FBgn0036278
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001107548.1
• Gene: gnrhr2/nmi / 100135416
• XenbaseID: XB-GENE-29077251
• Length: 373
• Species: Xenopus tropicalis
• Alignment Length: 306
• Identity: 94/306 - (30%)
• Similarity: 168/306 - (54%)
• Gaps: 24/306 - (7%)

  Fly   112 PQLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTW 176
            |..:.:..::|.|.....|.:...|:..:.:|        :.:...|.:..|:..||:||:|||:
 Frog    34 PTFTLAAKVRVGVTCCFFLIASFSNVAVLCSI--------SGKRCKSHLRVLILSLSVADLLVTF 90

  Fly   177 FCIIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCH 241
            ..:..:|.|...|||.|.||:||::...::|::|.:..|||:|.:||..|:.||:...:..:|..
 Frog    91 LVMPLDALWNVMVQWYAGELSCKVLNFGKLFAMYSAALVLVVISLDRHWAILYPLSFTSAGQRNR 155

  Fly   242 RLLGGTYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTADWQEQMYATFTLVFTFLLPLCI 306
            .:|...:|.||:|:.||.|:|.:...|.| .|.||.|||.:|..|||..|..||....|:.||.:
 Frog   156 IMLWTAWITSLLLASPQLFLFRLRTAPGV-NFTQCATHGSFTQHWQETAYNMFTFCTLFVTPLVV 219

  Fly   307 LFGTYMSTFRTISSSEKMFQGSKLANYSTAKLPTQTNRQRLIHKAKMKSLRISVVIIIAFLICWT 371
            :...|......|  .::|...::||.          ::..||.||::|:|::::||:::|::|||
 Frog   220 MIVCYTRILWEI--GKQMKHKNELAR----------SKNDLISKARLKTLKMTLVIVVSFMVCWT 272

  Fly   372 PYYVMMIMFMFLNPD--KRLGDDLQDAIFFFGMSNSLVNPLIYGAF 415
            |||::.:.:.| .|:  .:..:.|..::|.||:.::..:||:||.:
 Frog   273 PYYLLGLWYWF-QPEMINQTPEYLNHSLFLFGLLHTCTDPLVYGLY 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrzR	NP_001261755.1	7tmA_GnRHR_invertebrate	119..419	CDD:320506	93/299 (31%)
		TM helix 1	120..146	CDD:320506	5/25 (20%)
		TM helix 2	160..187	CDD:320506	10/26 (38%)
		TM helix 3	198..228	CDD:320506	11/29 (38%)
		TM helix 4	239..260	CDD:320506	8/20 (40%)
		TM helix 5	288..317	CDD:320506	8/28 (29%)
		TM helix 6	350..380	CDD:320506	13/29 (45%)
		TM helix 7	391..416	CDD:320506	8/25 (32%)
gnrhr2/nmi	NP_001107548.1	7tmA_GnRHR_vertebrate	41..325	CDD:320505	93/299 (31%)
		TM helix 1	42..68	CDD:320505	5/33 (15%)
		TM helix 2	74..101	CDD:320505	10/26 (38%)
		TM helix 3	112..142	CDD:320505	11/29 (38%)
		TM helix 4	153..174	CDD:320505	8/20 (40%)
		TM helix 5	201..230	CDD:320505	8/28 (29%)
		TM helix 6	251..281	CDD:320505	13/29 (45%)
		TM helix 7	293..318	CDD:320505	8/25 (32%)