DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and DAR5

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_201464.2	Gene:	DAR5 / 836795	AraportID:	AT5G66630	Length:	702	Species:	Arabidopsis thaliana

Alignment Length:	173	Identity:	37/173 - (21%)
Similarity:	60/173 - (34%)	Gaps:	39/173 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 DCSGRTEVGHIKCEKN--FELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCG--MQLHH-TCYV 315
            :|....|......|.|  ..:|.||...:.....:|:....||..|..|..|.  :.:|. ..:|
plant   326 ECRDEIEENEKLPEVNPPLSMCGGCNSAVKHEESVNILGVLWHPGCFCCRSCDKPIAIHELENHV 390

  Fly   316 RNSK-LYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFV--------CYACRLPLQ 371
            .||: .:.|..|:|.        |:....:::....|..|.....|.|        |.:|.....
plant   391 SNSRGKFHKSCYERY--------CYVCKEKKMKTYNIHPFWEERYCPVHEADGTPKCCSCERLEP 447

  Fly   372 KGEQF-MLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEED 413
            :|.:: .|.||:..|    ||            ||...:|.::
plant   448 RGTKYGKLSDGRWLC----LE------------CGKSAMDSDE 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	14/55 (25%)
		LIM	333..388	CDD:295319	12/63 (19%)
		Homeobox	427..480	CDD:278475
DAR5	NP_201464.2	RPW8	7..147	CDD:283345
		LIM_DA1	347..402	CDD:188782	14/54 (26%)
		DUF3633	488..700	CDD:289113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	47	0.796	Domainoid score	I4515
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000