DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and HB5

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_201334.1	Gene:	HB5 / 836656	AraportID:	AT5G65310	Length:	312	Species:	Arabidopsis thaliana

Alignment Length:	231	Identity:	57/231 - (24%)
Similarity:	96/231 - (41%)	Gaps:	47/231 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 FLAAAAAQHCG-FVGLDEEDLLRPRDG------RRGPKRPRTILTSQQRKQFKASF--DQSPKPC 450
            ||.:.|..:.. |..|:::..|....|      ....|:.|  |..:|.|..:.:|  |...:|.
plant    35 FLYSGAGDYSQMFDALEDDGSLEDLGGVGHASSTAAEKKRR--LGVEQVKALEKNFEIDNKLEPE 97

  Fly   451 RKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTND 515
            |||:  ||::.||..|.|.:||||:||:.|  .::.:::.|....:.........|...|.|:..
plant    98 RKVK--LAQELGLQPRQVAIWFQNRRARWK--TKQLERDYGVLKSNFDALKRNRDSLQRDNDSLL 158

  Fly   516 KEDKCVKQEL------GGDSSGYLGGLDSTFASQPLNPNL----------PFSPDDYPANSNDSF 564
            .:.|.:|.:|      |.:.:|.|..:::..:....|..|          |..|.|.|
plant   159 GQIKELKAKLNVEGVKGIEENGALKAVEANQSVMANNEVLELSHRSPSPPPHIPTDAP------- 216

  Fly   565 CSSDLSLD-------GSNF-DQLDDDADSLSLNNLE 592
             :|:|:.:       ..|| |...|.:||.::.|.|
plant   217 -TSELAFEMFSIFPRTENFRDDPADSSDSSAVLNEE 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	22/54 (41%)
HB5	NP_201334.1	Homeobox	79..125	CDD:278475	20/47 (43%)
HB5	NP_201334.1	HALZ	127..168	CDD:280364	6/40 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910