Protein Alignment Lmx1a and lhx2b

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001035099.3
• Gene: lhx2b / 791744
• ZFINID: ZDB-GENE-051220-1
• Length: 427
• Species: Danio rerio
• Alignment Length: 326
• Identity: 96/326 - (29%)
• Similarity: 138/326 - (42%)
• Gaps: 75/326 - (23%)

  Fly   254 SADCSGRTEVGHIKCEKNF--------ELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLH 310
            ||..|...::|  :.|.|.        .||.|||.||.||:.:...|..||.:||.||.|.:.|.
Zfish    57 SATISSAIDMG--ETETNMPSISGDRVALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLE 119

  Fly   311 H--TCYVRNSKLYCKMDYDRLFGV-KCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQK 372
            .  ||:.::..:|||.||.|.|.| :|:.|...|...|:||| ..:.|:||.||.|..|...|..
Zfish   120 SELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMR-ARDLVYHLNCFTCTTCNKMLTT 183

  Fly   373 GEQFMLRDGQLFCYRH----------------DLEKEMFLAAAAAQHCGFV-GLDEEDLLRPRDG 420
            |:.|.::|..::|..|                |:.....|::.......:. |::.....|||.
Zfish   184 GDHFGMKDSLVYCRLHFETLIQGDFPTHFNHTDVAPNKGLSSTGPLGLSYYNGVNTVQKGRPRK- 247

  Fly   421 RRGP-----------------------------------KRPRTILTSQQRKQFKASFDQSPKPC 450
            |:.|                                   ||.||.....|.:..|:.|..:..|.
Zfish   248 RKSPGPGADLAAYNAALSCNENDGDPMDRDSQYSSSQKTKRMRTSFKHHQLRTMKSYFAINHNPD 312

  Fly   451 RKVREALAKDTGLSVRVVQVWFQNQRAKMKK-IQR-------KAKQNGGSGGGSGSGRGTGNSSA 507
            .|..:.||:.|||:.||:||||||.|||.:: :.|       ||.......||:.||..:..|:|
Zfish   313 AKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKASDGSNLAGGTPSGPASEISNA 377

  Fly   508 T 508
            :
Zfish   378 S 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	23/53 (43%)
		LIM	333..388	CDD:295319	19/54 (35%)
		Homeobox	427..480	CDD:278475	23/52 (44%)
lhx2b	NP_001035099.3	LIM1_Lhx2	74..137	CDD:188853	23/62 (37%)
		LIM2_Lhx2_Lhx9	142..200	CDD:188763	20/58 (34%)
		COG5576	<267..389	CDD:227863	34/112 (30%)
		Homeobox	290..342	CDD:278475	23/51 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910