DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and hoxc13a

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_571618.1	Gene:	hoxc13a / 58059	ZFINID:	ZDB-GENE-000822-4	Length:	306	Species:	Danio rerio

Alignment Length:	153	Identity:	40/153 - (26%)
Similarity:	66/153 - (43%)	Gaps:	17/153 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 LPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLR---DGQLFCYRHDLEKEMFLAAAAAQH 403
            :|..|.|..:|:...|..  ..:...:|::..:.:.|.   |||::|.:...:         :.|
Zfish   161 VPGYLDMSVVPSISVHPE--PRHDALIPMEGYQHWALSNGWDGQVYCSKEQTQ---------SSH 214

  Fly   404 CGFVGLDEEDLLRPR--DGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVR 466
            .......:...|:|.  ..|||.|: |...|..|.|:.:..:..|....:..|..::..|.||.|
Zfish   215 LWKSPFPDVVPLQPEVSSYRRGRKK-RVPYTKIQLKELEKEYAASKFITKDKRRRISATTNLSER 278

  Fly   467 VVQVWFQNQRAKMKKIQRKAKQN 489
            .|.:||||:|.|.||...|:|.|
Zfish   279 QVTIWFQNRRVKEKKFVSKSKTN 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319	11/48 (23%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
hoxc13a	NP_571618.1	HoxA13_N	31..142	CDD:289085
hoxc13a	NP_571618.1	Homeobox	239..292	CDD:278475	17/53 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910