Protein Alignment Lmx1a and Isl2

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_065204.2
• Gene: Isl2 / 57233
• RGDID: 621849
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 338
• Identity: 109/338 - (32%)
• Similarity: 155/338 - (45%)
• Gaps: 53/338 - (15%)

  Fly   265 HIKCEKNFELCEGCGQKIHDRFLMNVG-DANWHEQCLACCYCGMQLHH--TCYVRNSKLYCKMDY 326
            |.|.:....:|.|||.:|||:|::.|. |..||..||.|..|...|..  ||:||:.|.|||.||
  Rat    17 HSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDY 81

  Fly   327 DRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHD-- 389
            .||||:||:.|.......:|||| ..:.|:|:.||.|..|...|..|::|.||:.:|.| |.|
  Rat    82 VRLFGIKCAQCQVGFSSSDLVMR-ARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLC-RADHG 144

  Fly   390 --LEKEMF--------LAAAAAQHCGFVGLDEEDLLRPRDGRRGPK--RPRTILTSQQRKQFKAS 442
              ||:...        |..|...|....|...:..||....::..|  |.||:|..:|....:..
  Rat   145 LLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQSSLRTHVHKQAEKTTRVRTVLNEKQLHTLRTC 209

  Fly   443 FDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAK-------MKKIQR-----KAKQNGGSGGG 495
            :..:|:|...::|.|.:.||||.||::|||||:|.|       ||::|:     ||...|.:|..
  Rat   210 YAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKASLQGLTGTP 274

  Fly   496 SGSGRGTGNSSATDDKDT------------------NDKEDKCVKQELGGDSSGYLG---GLDST 539
            ..:|....:.:|......                  :|.:....:|.:....||.||   |.|.|
  Rat   275 LVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVT 339

  Fly   540 FASQPLNPNLPFS 552
            ..|..| |:.|.|
  Rat   340 SLSSQL-PDTPNS 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	26/54 (48%)
		LIM	333..388	CDD:295319	20/54 (37%)
		Homeobox	427..480	CDD:278475	21/59 (36%)
Isl2	NP_065204.2	LIM1_Isl	27..81	CDD:188752	25/53 (47%)
		LIM2_Isl2	89..143	CDD:188855	20/55 (36%)
		HOX	191..247	CDD:197696	22/55 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910