Protein Alignment Lmx1a and lmx1bb

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001020338.2
• Gene: lmx1bb / 554360
• ZFINID: ZDB-GENE-050114-2
• Length: 375
• Species: Danio rerio
• Alignment Length: 417
• Identity: 156/417 - (37%)
• Similarity: 213/417 - (51%)
• Gaps: 91/417 - (21%)

  Fly   258 SGRTEVGHI---KCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSK 319
            ||:..:|.:   :|... .:||||.:.|.|||||.|.:::|||:||.|..|...|..:||.|..|
Zfish    14 SGQATLGVMLGTECHHQ-AVCEGCQRPISDRFLMRVNESSWHEECLQCAVCQQPLTTSCYFRERK 77

  Fly   320 LYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLF 384
            ||||.||.:||..|||.|...|.|.|.|||.: ..|:||.||.|..|...|:||::|:|:||||.
Zfish    78 LYCKYDYQQLFATKCSGCLEKIAPTEFVMRAL-ECVYHLNCFCCCVCDRQLRKGDEFVLKDGQLL 141

  Fly   385 CYRHDLEKEMFLAAAAAQHCGFVGLDEEDL---------LRPRDGRRG------------PKRPR 428
            | :.|.|:|..|       .|.|..|:.|.         ::|..|..|            |||||
Zfish   142 C-KSDYEREKDL-------LGSVSPDDSDSEKSEDEELDIKPEKGSGGTGKGDDGKDPRRPKRPR 198

  Fly   429 TILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSG 493
            ||||:|||:.|||||:.|.||||||||.||.:|||||||||||||||||||||:.|:.:|.
Zfish   199 TILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQ---- 259

  Fly   494 GGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGY---------LGGLDSTFASQPLNPNL 549
                          .:.:::.....:.:...:.|..:.|         :..|::.:::.|....|
Zfish   260 --------------QEQQNSQRLGQEVMSNRMEGMMNSYTPLAPAQQQMVALENGYSTDPFQQGL 310

  Fly   550 --PFSPDDY-PANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHSNPH 611
              |..|.|: ....|||.           |..:|.|....||::. ..::|.:|:
Zfish   311 TPPQMPGDHMNPYGNDSI-----------FHDIDSDTSLTSLSDC-FMASSDAGS---------- 353

  Fly   612 DMLANLNNSLINPIDKLYLMQNSYFSS 638
             |.|.:.    ||||:||.||:|||:|
Zfish   354 -MQARVG----NPIDRLYSMQSSYFAS 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	28/51 (55%)
		LIM	333..388	CDD:295319	27/54 (50%)
		Homeobox	427..480	CDD:278475	43/52 (83%)
lmx1bb	NP_001020338.2	LIM1_Lmx1b	33..85	CDD:188757	28/51 (55%)
		LIM2_Lmx1a_Lmx1b	92..146	CDD:188764	26/55 (47%)
		Homeobox	197..250	CDD:278475	43/52 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9077
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323174at33208
OrthoFinder	1	1.000	-	-		FOG0001820
OrthoInspector	1	1.000	-	-		otm24731
orthoMCL	1	0.900	-	-		OOG6_105498
Panther	1	1.100	-	-	O	PTHR24208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	1	1.000	-	-		X1182
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.910