Protein Alignment Lmx1a and esn

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001260760.1
• Gene: esn / 53557
• FlyBaseID: FBgn0263934
• Length: 1134
• Species: Drosophila melanogaster
• Alignment Length: 762
• Identity: 148/762 - (19%)
• Similarity: 224/762 - (29%)
• Gaps: 276/762 - (36%)

  Fly    28 ARF---LDNPNPGSMTASSGNSLHLSNSNNNLPTSISGNNSPTATASLTGQHQQHQQQQHQQQQQ 89
            |||   ...|.|.:.||.....          |:.:.....||.....:|     ..||..||||
  Fly   309 ARFDGHSKRPPPPAATAPKITQ----------PSQVIEKFKPTPAPRSSG-----NMQQAPQQQQ 358

  Fly    90 HPHQQHQQHQQQHAA-----------------STTPVPINSCPTPTGHSPLSSSSSNSNHNNNNN 137
            |||.....:..|..:                 |..|....|....|.|..:.|::|
  Fly   359 HPHPPSSSYYTQTESELLQIEAGGTGLTFASHSQRPESAISQVASTAHLDVPSAAS--------- 414

  Fly   138 NNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLG----------GAVAAAIA 192
            :.:|||                  |.|..:..||..||..|:..|..          .:||:.:.
  Fly   415 SGSGGS------------------AVSGGSGGAPESAGRFVSPLQRRHCQPPSHLPLNSVASPLR 461

  Fly   193 AAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNG-----NGNGNGNGNGGGAATASAAAASK 252
            .|:..:|||.                 :|:|..:.:.     ..|...:.:.|.|..........
  Fly   462 TASYKSAAAV-----------------AGHGFHHSHHQQLDFQRNSQSDDDSGCALEEYTWVPPG 509

  Fly   253 LSAD------------------------------------------CSG-----RTEV------- 263
            |..|                                          |..     |.|:
  Fly   510 LRPDQVRLYFSQLPDDKVPYVNSPGEKYRVKQLLHQLPPQDNEVRYCHSLSDEERKELRIFSAQR 574

  Fly   264 -------GHIKCEKNFELCEGCGQKIHDR----FLMNVG-DANWHEQCLACCYCGMQLHHTCYV- 315
                   |.::...:...|:||.:.:...    |...:| ...||..|..|..|...|....|.
  Fly   575 KREALGRGAVRLLSDERPCKGCEEPLSGGDIVVFAQRLGAQLCWHPGCFVCSVCKELLVDLIYFQ 639

  Fly   316 RNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRD 380
            |:..|||...:......:||:|...|...|..  ......:|:..|.|..|...| .|:::::|:
  Fly   640 RDGNLYCGRHHAETQKPRCSACDEIIFSDECT--EAEGRTWHMKHFACQECEHQL-GGQRYIMRE 701

  Fly   381 GQLFCYRHDLEKEMFLAAAAAQHCG-FVGLDEEDLLRPRDGRR-------------------GPK 425
            |:.:|..  ....||  |....:|| .:|:|:..:  ..||:.                   .|.
  Fly   702 GKPYCLA--CFDTMF--AEYCDYCGEVIGVDQGQM--SHDGQHWHATDQCFSCCTCRCSLLGRPF 760

  Fly   426 RPR--TILTSQQRKQFKASFDQSPKPCRKVREALAKDT--GLSVRVVQVWFQNQRAKMKKIQRKA 486
            .||  ||..|     ...|..:.|.|         .||  |..:|      ...||.......|:
  Fly   761 LPRRGTIYCS-----IACSKGEPPTP---------SDTSSGPQLR------PTHRASTSSQIAKS 805

  Fly   487 KQNGGS-----GGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLDSTFASQPLN 546
            .:.||.     |..:..|......||.|..:..:::    :.|..|.:...|||
  Fly   806 PRRGGERERDPGRKAHHGHPKATGSAGDLLERQERQ----RMEAAGVADLLLGG----------- 855

  Fly   547 PNLPFSPDDYPAN-----------SNDSFCSSDLSLDGSN-----------FDQLDDDADSLSLN 589
             .:|..|  .||:           |.|:.|:.|.|:.|..           ..:.||.....|::
  Fly   856 -GVPGMP--RPAHPPPIDLTELGISLDNICAGDKSIFGDTQTLTNSMPDMLLSKADDSHSYQSID 917

  Fly   590 NLELQSTSSSG-NQHSHSHSN------------PHD----MLANLNN 619
            .:.|.|.|:|. .|.:...:|            |||    :.||..|
  Fly   918 KINLNSPSNSDLTQSTQELANELELDNEPVRELPHDGYEQLFANNRN 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	16/57 (28%)
		LIM	333..388	CDD:295319	14/54 (26%)
		Homeobox	427..480	CDD:278475	14/56 (25%)
esn	NP_001260760.1	PET_Prickle	492..588	CDD:193602	8/95 (8%)
		LIM1_Prickle	593..651	CDD:188799	16/57 (28%)
		LIM2_Prickle	656..711	CDD:188802	14/59 (24%)
		LIM3_Prickle	716..774	CDD:188804	12/64 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910