Protein Alignment Lmx1a and pk

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Alignment Length: 829
• Identity: 151/829 - (18%)
• Similarity: 242/829 - (29%)
• Gaps: 315/829 - (37%)

  Fly    78 QHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSP-------------------- 122
            :.:::..:|:...|....:|.||:......|.|.|......|..|
  Fly   239 EQEEESPEQEAPKPALPPKQKQQRPVPPLPPPPANRVTQDQGTQPAAPQVPLQPLTAGDLQFLNL 303

  Fly   123 -LSSSSSNSNHNNNNNNNNGGSSSNNLHSAC--NTLTAAAVAAASAAAVAAP------------- 171
             |...|...:.....:.::...:.|.|.::.  ...|.||...::......|
  Fly   304 SLRQRSLPRSMKPFKDAHDISFTFNELDTSAEPEVATGAAQQESNEPISRTPLTQISYLQKIPTL 368

  Fly   172 ----SPAGTSVATSQL---GG----AVAAAIAAAAAAAAAATTPTSTGPAA-------------T 212
                ||:|..:||...   ||    :.::|.|..||.|||...|||..|..             .
  Fly   369 PRHFSPSGQGLATPPALGSGGMGLPSSSSASALYAAQAAAGILPTSPLPLQRHQQYLPPHHQQHP 433

  Fly   213 GSGNANGSGNGNGNGNGNGNGNGNG-------------------------------------NGG 240
            |:|...|.|:|...|...|.....|                                     ..|
  Fly   434 GAGMGPGPGSGAAAGPPLGPQYSPGCSANPKYSNAQLPPPPHHHHQLSPALSTPSPPSLLHHPAG 498

  Fly   241 GAATASAAA-------------------------------------------------------- 249
            |.::|||.|
  Fly   499 GTSSASAHAPFLGGPHMDMQRQSHSDDDSGCALEEYTWVPPGLRPDQVRLYFSQIPDDKVPYVNS 563

  Fly   250 --------------------------------------ASKLSADCSGRTEVGHIKCEKNFELCE 276
                                                  :::...|..||   |:::...:...|:
  Fly   564 PGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRKRDALGR---GNVRQLMSARPCD 625

  Fly   277 GCGQKIHDRFLMNVGD-----------ANWHEQCLACCYCGMQLHHTCYV-RNSKLYCKMDYDRL 329
            ||..      |::.||           |:||..|.||..|...|....|. |:.::||...:...
  Fly   626 GCDD------LISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAET 684

  Fly   330 FGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEM 394
            ...:||:|...||..|..  ......:|:..|.|:.|...| .|:::::|:|:.:|. |..:
  Fly   685 LKPRCSACDEIILADECT--EAEGRAWHMNHFACHECDKQL-GGQRYIMREGKPYCL-HCFD--- 742

  Fly   395 FLAAAAAQHCGF----VGLDEEDLLRPRDG--------------------------RRG------ 423
               |..|::|.:    :|:|:..:  ..||                          |||
  Fly   743 ---AMFAEYCDYCGEAIGVDQGQM--SHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSI 802

  Fly   424 ------PKRPR------TILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQR 476
                  |..|.      ...|.....|......|:|.|.|......:....:|.:..|   |:|.
  Fly   803 ACSKGEPPTPSDSSGTGMYTTPTPPTQRVRPHPQAPLPARIPSSHASSSPPMSPQQQQ---QHQA 864

  Fly   477 A-KMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQEL-------GGDSSGYL 533
            . .....|.:::|...:||.....:    |.|..|.|..      |.::|       |||.:.:.
  Fly   865 TFNQAMYQMQSQQMEAAGGLVDQSK----SYAASDSDAG------VVKDLEHGGHMGGGDLTDFS 919

  Fly   534 GGLDSTFASQPLNP-NLP--FSPDDYPANSNDSFCSSDLSLDG-SNFDQLDDDADSLSLNNLELQ 594
            ||..|: .||.|:| |.|  |.|...|.       ..:|..|| .||:::..:.|:       ..
  Fly   920 GGRASS-TSQNLSPLNSPGDFQPHFLPK-------PMELQRDGVYNFNEMSSNLDA-------AW 969

  Fly   595 STSSSGNQHSHSH--SNPHD-MLANLNNSLINPIDKLYLMQNSYFSSEH 640
            |...:.:.|....  .|||. .:..|...|:.|...:..:...:..|.|
  Fly   970 SAKPTNSYHLQRQLLENPHTASMPELAGKLVAPPAHMQHLSQLHAVSSH 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	18/63 (29%)
		LIM	333..388	CDD:295319	15/54 (28%)
		Homeobox	427..480	CDD:278475	11/59 (19%)
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	4/97 (4%)
		LIM1_Prickle	624..682	CDD:188799	18/63 (29%)
		LIM2_Prickle	687..742	CDD:188802	16/58 (28%)
		LIM3_Prickle	747..805	CDD:188804	8/59 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910