DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and toy

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	244	Identity:	69/244 - (28%)
Similarity:	101/244 - (41%)	Gaps:	50/244 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   410 DEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQN 474
            ||:..:|.| .:|..:|.||..:::|....:..|:::..|....||.||...||....:||||.|
  Fly   252 DEDSQMRLR-LKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSN 315

  Fly   475 QRAKMKKIQRKAKQNGGSGGGSGSGR--------GTGNSS--ATDDKDT--------NDKE---D 518
            :|||.::.::...|...:....||||        ||..||  ||.:..|        |..|   .
  Fly   316 RRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSS 380

  Fly   519 KCVKQELGGDSSG--YLGG-LDSTFAS------QPLNPNLP--------FSPDDYP-ANSNDSFC 565
            ..|...|...|:|  .||| .::|..|      ||..|.||        :|....| |...:::.
  Fly   381 ALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYN 445

  Fly   566 SSDLSLDGSNFDQLDDDA----DSLSLNNLELQSTSSSGNQHSHSHSNP 610
            ||..|:..|...|.|...    |.|||.:..:.:      .|.::..||
  Fly   446 SSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSA------HHRNTACNP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	19/52 (37%)
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	36/115 (31%)
		Homeobox	269..322	CDD:395001	19/52 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910