Protein Alignment Lmx1a and Ptx1

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 112/543 - (20%)
• Similarity: 183/543 - (33%)
• Gaps: 137/543 - (25%)

  Fly   143 SSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGA-VAAAIAAAAAAAAAATTPTS 206
            ||:..|.....|.....|.:.:...:.|.|...|.:....|..| .|....:|.:|.:|.||.|:
  Fly    23 SSATALGPGGLTNGGGGVVSGALNGLEAMSAESTGLCLQDLVSAGTANGAGSAGSAESATTTSTA 87

  Fly   207 TGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKN 271
            ....:|||...||.|:.. :|..:.:.:.:.:...::.:.:.|.|.|....|    :.|:.....
  Fly    88 LSSGSTGSSTVNGGGSST-SGTEHLHSHHSLHDSSSSVSISPAISSLMPISS----LSHLHHSAG 147

  Fly   272 FELCEGCGQKIHD----------------RFLMNVGD-ANWHEQCLACCYCGMQLHHTCYVRNSK 319
            .:|..|..|..|.                |.....|| .:.|....|             |.||
  Fly   148 QDLVGGYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSHSSMTA-------------VANS- 198

  Fly   320 LYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLF 384
                :|...|...:.||           ...|.|                       ..||
  Fly   199 ----LDSTHLNNFQTSS-----------TSSISN-----------------------RSRD---- 221

  Fly   385 CYRHDLEKEMFLAAAAAQHCGFVGLDE------EDLLRPRDGRRGPKRPRTILTSQQRKQFKASF 443
              |.|..:.:.......::....|.||      |:....:..:| .:|.||..||||.::.:.:|
  Fly   222 --RKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDKKNKR-QRRQRTHFTSQQLQELEHTF 283

  Fly   444 DQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSAT 508
            .::..|....||.:|..|.|:...|:|||:|:|||.:|.:|.|.....:.....||.||......
  Fly   284 SRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVAAADFKSGFGTQFMQPF 348

  Fly   509 DDKDTNDKEDKCVKQELGGDSSGYLGGLDSTFASQPLN-----PN-LPFSPDDYPANSNDSFCSS 567
            .|                          ||.::|.|.|     |: |...|..:|.|...|..:.
  Fly   349 AD--------------------------DSLYSSYPYNNWTKVPSPLGTKPFPWPVNPLGSMVAG 387

  Fly   568 DLSLDGSNFDQLDDDADSLSLNNLEL------QSTSSSGNQHSHSHSNPHDMLAN---------- 616
            :...:..|.........::|:||..:      .|.|::.|..:.....|:...||
  Fly   388 NHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYTTPANPYMYRSAAEP 452

  Fly   617 -LNNSLINPIDKLYLMQNSYFSS 638
             :::|:.:.|..|.|....:.|:
  Fly   453 CMSSSMSSSIATLRLKAKQHASA 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	12/68 (18%)
		LIM	333..388	CDD:295319	6/54 (11%)
		Homeobox	427..480	CDD:278475	21/52 (40%)
Ptx1	NP_001138130.2	Homeobox	268..320	CDD:278475	21/51 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000