Protein Alignment Lmx1a and CG18599

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 137/636 - (21%)
• Similarity: 208/636 - (32%)
• Gaps: 224/636 - (35%)

  Fly     6 PMPTNLNPVGG--SLYSLQQNHGGARFLDNPNPGSMTA---SSGNSLHLSNSNNNLPTSISGNNS 65
            |...:.||:..  :|::.|.:.||:      ..||..|   ..|..:|.....::...:.:...:
  Fly     5 PSKYHANPLSHFLALHNTQASGGGS------GGGSSVAGLGGLGGGIHAHGQPHHAALAAAAAAA 63

  Fly    66 PTATASLTGQHQQHQQQQHQQQQQHPHQQHQQHQQ---QHAASTTPVPINSCPTPTGHSPLSSSS 127
            ...:|..:....:||||.||.|||...|||..|||   .|.....|.|    ||||
  Fly    64 VAVSAGQSSYQMEHQQQHHQLQQQQQQQQHHHHQQLHTHHQDGHHPHP----PTPT--------- 115

  Fly   128 SNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGAVAAAIA 192
              :.:||||::::..|||:|.:|......|||.|.|::.|              ||       |.
  Fly   116 --TGNNNNNSSSSSNSSSHNSNSNHREQLAAAAATATSHA--------------QL-------IE 157

  Fly   193 AAAAAAAAATTPTSTGPAATG------------------SGNANGSGN-----GNGNGNGNGNGN 234
            ||||.::.....:.|..|..|                  :.|..|..|     .|.|.|.|.|.|
  Fly   158 AAAAHSSLDVGKSFTIAAILGLQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSNPNNNNNNNNN 222

  Fly   235 GNGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQC 299
            |..|.|...::.:               |.:..|:.    ..|.|:.:|
  Fly   223 GGSNSGNNNSSPS---------------VNNFNCDS----VAGNGRYLH---------------- 252

  Fly   300 LACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCY 364
                  |...|                                       |.|    |...|...
  Fly   253 ------GGHQH---------------------------------------PHP----HQAGFAAV 268

  Fly   365 ACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGRRGP---KR 426
            |..:.....   .|:..|....:|..:::..|:.            :.:.|:....::..   ||
  Fly   269 AAAVGAAPS---ALQSLQQLHQQHHAQQQATLSF------------QREKLKSDSHKKSALKNKR 318

  Fly   427 PRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKK---------- 481
            .|||.|.:|.:..:|.|::........|..||....|:...|:|||||:|.|.:|
  Fly   319 VRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRL 383

  Fly   482 -IQRKAKQNGGSGGGS------------GSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYL 533
             :.|:.:..|.|..|:            .:.|..|.|:|:......|.||......|.|
  Fly   384 ALIRQTQLPGTSLLGNQVSVSANAAHSVSTERTNGCSAASPSLQEEDNEDSKHSLSLSG------ 442

  Fly   534 GGLDSTFASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDDAD 584
                   |..||:        ...:.|:.|.|:.  ||||   |.|.|.::
  Fly   443 -------ALPPLS--------RAQSESDLSICND--SLDG---DSLMDGSE 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	5/51 (10%)
		LIM	333..388	CDD:295319	7/54 (13%)
		Homeobox	427..480	CDD:278475	19/52 (37%)
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	19/51 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000