Protein Alignment Lmx1a and Hmx

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 115/593 - (19%)
• Similarity: 172/593 - (29%)
• Gaps: 263/593 - (44%)

  Fly    32 DNPNPGSMT----ASSGNSLHLSNSNNNLPTSISGNNSPTATASLTGQHQ--------------- 77
            :.||..:.|    ||.||..|.|.|...:|.::..::.....:|| |.|.
  Fly    53 NTPNTAAGTPTTSASGGNHFHHSPSGGAVPPAVLHHHLQHHLSSL-GSHPVALHHALHTFGHLHP 116

  Fly    78 ----------QHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPI-----NSCPTPTGHSPLSSSS 127
                      ||......||||...|..|||||.|....:| |:     |......|||..:::|
  Fly   117 AHGATHPALLQHALTPTGQQQQQQLQVQQQHQQSHVERLSP-PMKSPERNGGDEVQGHSLNNNNS 180

  Fly   128 SNSNHNN--------------------NNNNNNGGSS---SNNLHSACNTLTAAAVAAA------ 163
            ...||||                    ||:|::.|||   .....:..|..|:.::::.
  Fly   181 KALNHNNTCASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSILSRSEP 245

  Fly   164 ----SAAAVAAPSP------AG---TSVATSQLG-----GAVAAAIAAAAAAA------------ 198
                .||.:..|.|      ||   .:...|:||     ||:|...||.....
  Fly   246 AKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWPWAPQRLPFHS 310

  Fly   199 ----AAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASAAAASKLSADCSG 259
                :::|..|...|:.|.....|.:.|.|                  .|||:..|||..:.
  Fly   311 PTHDSSSTNTTENPPSPTSMSPNNNNNNSN------------------TTASSNQASKSPSH--- 354

  Fly   260 RTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKM 324
                                ..:|..: ..:|.....:|         |..|..:.:..:
  Fly   355 --------------------HPLHPLY-HPLGSQQQQQQ---------QQQHQQHPQQQQ----- 384

  Fly   325 DYDRLFGVKCSSCCHAILPQE-----------------------LVMRPIPNFVFHLPCFVCYAC 366
                          |   ||:                       |...|.|    ||
  Fly   385 --------------H---PQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHP----HL-------- 420

  Fly   367 RLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFV------GLDE--EDLLRPRDGRRG 423
                                             ...|.|::      ..||  |:::...||..|
  Fly   421 ---------------------------------TGSHGGYLLPSSSNESDEEGEEIIEEDDGTDG 452

  Fly   424 P---------------KRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQ 473
            |               |:.||:.:..|..|.:::||.........|..||....|:...|::|||
  Fly   453 PSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQ 517

  Fly   474 NQRAKMKK 481
            |:|.|.|:
  Fly   518 NRRNKWKR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	5/51 (10%)
		LIM	333..388	CDD:295319	8/77 (10%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
Hmx	NP_001262674.1	Homeobox	471..524	CDD:278475	17/52 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000