Protein Alignment Lmx1a and ems

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 126/633 - (19%)
• Similarity: 175/633 - (27%)
• Gaps: 278/633 - (43%)

  Fly     7 MPTNLNPVGGSLYSLQQNHGGARFLDNPNPGSMTASSGNSL-HLSNSNNNLP--TSISGNNSPTA 68
            |||....:|.|:.|:..|             .::.:.|||. .||...:..|  .::.|:...|.
  Fly    17 MPTPKQKIGFSIESIVGN-------------DVSTAGGNSTPDLSGPQSPPPGERNVPGSPPQTP 68

  Fly    69 TASLT------GQH------------QQHQQQQH-QQQQQHPH----QQHQQH-----QQQHAAS 105
            .|:||      ..|            ..|.|||| |....|||    |||..|     ||||..
  Fly    69 PATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQHLQAPHPHPHLSPAQQHVLHQHLLMQQQHPG- 132

  Fly   106 TTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAA 170
                      ||..|..:.......:||...     .|..:.|.:..:..|.....|.|.....:
  Fly   133 ----------TPKSHQDIQELLQRLHHNAAM-----ASGLSPLQTRLSPETEQPQMAVSLKRERS 182

  Fly   171 PSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNG 235
            |:|.           |:..|...|.......|.|.|..|.
  Fly   183 PAPP-----------AMEQAENPAQRIQPPHTPPKSVSPQ------------------------- 211

  Fly   236 NGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCL 300
                  ::..|::....:|:.
  Fly   212 ------SSQPSSSPTLLISSP-------------------------------------------- 226

  Fly   301 ACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNF----VFH---- 357
                                                  ||..||:...:|.||:    :.|
  Fly   227 --------------------------------------HATPPQQQQQQPPPNYPKPAMMHPGGA 253

  Fly   358 --------------------------------------LPCFVCYACRLPLQ------KGEQFM- 377
                                                  ||.::.....||.|      ...||.
  Fly   254 GPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQM 318

  Fly   378 ---LRDGQLFCYRHDLEKEMFLAAA------AAQHCGFVGLDEEDL-----LRPRDGR------- 421
               |:.|      |.|......|||      |||.....|:..:..     |..|.||
  Fly   319 AAALQAG------HVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFP 377

  Fly   422 --------RGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAK 478
                    |.|||.||..:..|..:.:.:|:.:.......|:|||::..||...|:|||||:|.|
  Fly   378 GSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTK 442

  Fly   479 MKKIQRKAKQNGGSGGGSGSGRGTGNSSA-TDDKDTNDKE-DKCVKQE 524
            .|::|    |....||..||.|...|.|. .||.:..|.| |:|...|
  Fly   443 HKRMQ----QEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMDECPSDE 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	0/51 (0%)
		LIM	333..388	CDD:295319	17/110 (15%)
		Homeobox	427..480	CDD:278475	18/52 (35%)
ems	NP_731868.1	Homeobox	392..444	CDD:278475	18/51 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910