DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lmx1a and isl1b

DIOPT Version :9

Sequence 1:NP_729801.1 Gene:Lmx1a / 39406 FlyBaseID:FBgn0052105 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_001002043.1 Gene:isl1b / 415131 ZFINID:ZDB-GENE-040624-1 Length:323 Species:Danio rerio


Alignment Length:218 Identity:79/218 - (36%)
Similarity:118/218 - (54%) Gaps:18/218 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   275 CEGCGQKIHDRFLMNVG-DANWHEQCLACCYCGMQLHH--TCYVRNSKLYCKMDYDRLFGVKCSS 336
            |.|||.:|.|||::.|. |..||.:||.|..|...|..  ||::|:.|.:|:..|.||...||:.
Zfish    19 CVGCGLEILDRFIVRVSPDLEWHARCLKCAECHQFLDESCTCFIRDGKTFCREHYSRLSTSKCAK 83

  Fly   337 CCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAA 401
            |..|.:.:|.|||...| ::|:.||.|..|..||..|::::|:||||.|..|..:    |.:|:.
Zfish    84 CDKAFISKEFVMRSQVN-IYHVQCFRCEGCNRPLLSGDEYVLQDGQLLCTDHHNK----LMSASI 143

  Fly   402 QHCGFVGLDEEDL--------LRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALA 458
            ......|...|::        ::.|..|  ..|.||:|:..|....:..:..:|:|...::|.|.
Zfish   144 NQQKEAGDPSEEIKSTLSWSSMQRRSER--ATRVRTVLSETQLCMLQTCYTANPRPDALMKEQLV 206

  Fly   459 KDTGLSVRVVQVWFQNQRAKMKK 481
            :.||||.||::|||||:|.|.||
Zfish   207 EMTGLSPRVIRVWFQNKRCKDKK 229

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lmx1aNP_729801.1 LIM1_Lmx1b 275..327 CDD:188757 22/54 (41%)
LIM 333..388 CDD:295319 23/54 (43%)
Homeobox 427..480 CDD:278475 21/52 (40%)
isl1bNP_001002043.1 LIM1_Isl 19..73 CDD:188752 22/53 (42%)
LIM 81..135 CDD:295319 22/54 (41%)
HOX 174..228 CDD:197696 22/53 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.