DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and stck

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster

Alignment Length:	156	Identity:	39/156 - (25%)
Similarity:	63/156 - (40%)	Gaps:	44/156 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 GHIKCEKNFEL-----CEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCK 323
            |...||::|.:     |..||:.:..| ::....|:||.||..|..|..:|....:::|.
  Fly    66 GRKYCERDFHVLFAPCCNKCGEFVIGR-VIKAMSASWHPQCFRCQLCAKELADCGFIKNQ----- 124

  Fly   324 MDYDRLFGVKCSS-----------C--CHAILPQELVMRPIPNF---VFHLPCFVCYACRLPLQK 372
               :|....:|::           |  ||.::.:|    |: .|   |:|...|.|.||...|..
  Fly   125 ---NRALCHECNAKVKAEITGRYVCQKCHGLIDEE----PL-RFRGEVYHGYHFSCTACGTELDS 181

  Fly   373 -GEQFMLRDG-------QLFCYR-HD 389
             ..:...|.|       :|:|.| ||
  Fly   182 TAREVKSRPGLAANDMNELYCLRCHD 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	13/51 (25%)
		LIM	333..388	CDD:295319	19/79 (24%)
		Homeobox	427..480	CDD:278475
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	4/12 (33%)
		LIM2_PINCH	82..133	CDD:188718	14/59 (24%)
		LIM3_PINCH	146..206	CDD:188719	18/64 (28%)
		LIM4_PINCH	212..265	CDD:188720
		LIM5_PINCH	273..326	CDD:188721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910