DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and zen2

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	204	Identity:	50/204 - (24%)
Similarity:	76/204 - (37%)	Gaps:	47/204 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   425 KRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQN 489
            ||.||..:|.|..:.:..|..:....|..|..:::...|:.|.|::||||:|.|:||   ...:.
  Fly    44 KRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRRMKLKK---STNRK 105

  Fly   490 GGSGGGSGSGRGTGNSSATDDKD-----------TNDKEDKCVKQELGG-----------DSSGY 532
            |..|..:.|...:..||....||           ..:.|...::|...|           .|..|
  Fly   106 GAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHGVLEEGQITPPYQSYDY 170

  Fly   533 L---------------GGLDSTFASQ--PLNPNLPFSPDDYPANSND-----SFCSSDLSLDGSN 575
            |               ...|:.:||.  .|.|.:|.:.:....|:.|     :||....|...|:
  Fly   171 LHEFSPEPMALPQLPFNEFDANWASSWLGLEPTIPIAENVIEHNTQDQPMIQNFCWDSNSSSASS 235

  Fly   576 FDQLDDDAD 584
            .|.||.|.|
  Fly   236 SDILDVDYD 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	16/52 (31%)
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	16/52 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910