DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and mnx2a

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001009886.2	Gene:	mnx2a / 406205	ZFINID:	ZDB-GENE-040415-1	Length:	309	Species:	Danio rerio

Alignment Length:	171	Identity:	45/171 - (26%)
Similarity:	64/171 - (37%)	Gaps:	43/171 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 LAAAAAQHCGFV-------------------GLDEEDLLR--------------PRDGRRGP-KR 426
            :.|..|||..|.                   .|..|..||              |:.|..|. :|
Zfish    88 ITALGAQHPSFAYSGFTQPYPDHLKAAAMAGSLPLEHWLRAGLIMPRLADYSGAPQSGLIGKCRR 152

  Fly   427 PRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGG 491
            |||..||||..:.:..|..:....|..|..:|....|:...|::||||:|.|.|: .||||:...
Zfish   153 PRTAFTSQQLLELENQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKR-SRKAKEQAA 216

  Fly   492 --------SGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQE 524
                    ||......:.....||.|:.:..|.|::..:.|
Zfish   217 QLETDGCKSGKRGNKPKDLSRCSAHDEDEDLDPEEEAEEDE 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	19/52 (37%)
mnx2a	NP_001009886.2	Homeobox	153..206	CDD:278475	19/52 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910