DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and zgc:56628

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_956566.1	Gene:	zgc:56628 / 393242	ZFINID:	ZDB-GENE-040426-1099	Length:	172	Species:	Danio rerio

Alignment Length:	173	Identity:	61/173 - (35%)
Similarity:	87/173 - (50%)	Gaps:	25/173 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 LSADCSGRTEVGHIKC-EKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHH---TC 313
            :::.|:  |:..|::. ...::.|.|||.||.||||:...|..||..||.|..|..||..   :|
Zfish    13 VNSACN--TQAAHVRMGALAWKRCVGCGCKISDRFLLFALDGYWHCHCLKCSCCQAQLAEIGSSC 75

  Fly   314 YVRNSKLYCKMDYDRLFGVK--CSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQF 376
            :.:...:.||.||.||||..  |.:|..:|...|:|||...| |||:.||||..|...|..|::|
Zfish    76 FTKRGLILCKSDYLRLFGHSGACRACGTSIPANEMVMRAQGN-VFHVKCFVCSICHNQLVPGDRF 139

  Fly   377 MLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRD 419
            ...:|:|:|.|.        .:||::|        .|.||..|
Zfish   140 HYANGKLYCERD--------KSAASEH--------SDSLREHD 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	23/54 (43%)
		LIM	333..388	CDD:295319	22/56 (39%)
		Homeobox	427..480	CDD:278475
zgc:56628	NP_956566.1	LIM	34..88	CDD:295319	22/53 (42%)
zgc:56628	NP_956566.1	LIM2_LMO4	98..152	CDD:188773	23/62 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910