DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lmx1a and emx1

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_937787.1	Gene:	emx1 / 378964	ZFINID:	ZDB-GENE-031007-7	Length:	231	Species:	Danio rerio

Alignment Length:	180	Identity:	41/180 - (22%)
Similarity:	61/180 - (33%)	Gaps:	63/180 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   343 PQELVMRPIPNFVF-----HLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQ 402
            |....:.|.|..||     |.|                       |..:.|.      |.:|..|
Zfish    49 PAGRALYPNPELVFSETVNHAP-----------------------LSMHPHQ------LGSAPLQ 84

  Fly   403 HCGFVG---------------------------LDEEDLLRPRDGRRGPKRPRTILTSQQRKQFK 440
            |..|.|                           :.::.||......|.|||.||..:..|..:.:
Zfish    85 HPHFFGTQHREPLNFYPWVLRNRFFGHRFQGNDVSQDTLLLHGPFARKPKRIRTAFSPSQLLRLE 149

  Fly   441 ASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNG 490
            .:|:::.......|:.||....||...|:|||||:|.|.|:  :|.::.|
Zfish   150 RAFEKNHYVVGAERKQLANSLSLSETQVKVWFQNRRTKYKR--QKLEEEG 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319	8/49 (16%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
emx1	NP_937787.1	COG5576	82..>192	CDD:227863	28/111 (25%)
		Homeobox	137..189	CDD:278475	17/51 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..231		1/5 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910