DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and Lmo4

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001009708.1	Gene:	Lmo4 / 362051	RGDID:	1305670	Length:	165	Species:	Rattus norvegicus

Alignment Length:	157	Identity:	60/157 - (38%)
Similarity:	78/157 - (49%)	Gaps:	24/157 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 NGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLAC 302
            |.|.::......|..||                 ::.|.|||.||.||||:...|:.||.:||.|
  Rat     3 NPGSSSQPPPVTAGSLS-----------------WKRCAGCGGKIADRFLLYAMDSYWHSRCLKC 50

  Fly   303 CYCGMQLHH---TCYVRNSKLYCKMDYDRLFGVK--CSSCCHAILPQELVMRPIPNFVFHLPCFV 362
            ..|..||..   :||.::..:.|:.||.||||..  ||:|..:|...|||||...| |:||.||.
  Rat    51 SCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGN-VYHLKCFT 114

  Fly   363 CYACRLPLQKGEQFMLRDGQLFCYRHD 389
            |..||..|..|::|...:|.||| .||
  Rat   115 CSTCRNRLVPGDRFHYINGSLFC-EHD 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	23/54 (43%)
		LIM	333..388	CDD:295319	25/56 (45%)
		Homeobox	427..480	CDD:278475
Lmo4	NP_001009708.1	LIM1_LMO4	23..77	CDD:188772	22/53 (42%)
Lmo4	NP_001009708.1	LIM2_LMO4	87..141	CDD:188773	27/56 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910