Protein Alignment Lmx1a and lim-9

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001300395.1
• Gene: lim-9 / 3565712
• WormBaseID: WBGene00006407
• Length: 793
• Species: Caenorhabditis elegans
• Alignment Length: 808
• Identity: 134/808 - (16%)
• Similarity: 228/808 - (28%)
• Gaps: 306/808 - (37%)

  Fly     1 MLEFYPMPTNLNPVGGSLYSLQQNHGGARFLDNPNPGSMTASSGNSLHLSNSNNNL----PTSIS 61
            :::.|.||.|.|.      ..:::|...|.:|                :..:...|    |...|
 Worm    52 VVDIYDMPENNNA------QEKEDHYTKRAID----------------IGETKKRLELLPPPPTS 94

  Fly    62 GNNSPTATASLTGQHQQHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSPLSSS 126
            .:..||::.|:..:....::.|..::|               ||...|.:.. .||.....||:.
 Worm    95 SSPRPTSSNSIIQKSDGKRKDQKNEKQ---------------ASPIIVEVYD-DTPQSKMMLSTM 143

  Fly   127 SS----NSNHNNNNNNNNGG-------------SSSNNLHSACNTLTAAAVAAASAAAVAAPSPA 174
            ::    ..|:|:||||:|.|             |..|......|....|.|..........|
 Worm   144 NNPYRGGGNNNSNNNNSNHGMVIEDVTDDPEYSSYGNENEKPENEEEGAFVEYEKLDKTEDP--- 205

  Fly   175 GTSVATSQLGGAVAAAIAAAAAAAAAATT-----PTSTGPAATGSGNANGS-------------- 220
                          ||.....|..|...|     |:...|...|||:::||
 Worm   206 --------------AAFKVCQATTAVNRTYNNIRPSYRMPIGGGSGSSSGSISREIRIESMNLTD 256

  Fly   221 ----------------------------------------------------------GNGNGNG 227
                                                                      .:|....
 Worm   257 VEDGARCRDKECHLGWKQHPWRKVCVHCKSDRSDHELPPNQALNVYNRLGIQPPAGMPQSGVAEP 321

  Fly   228 NGNGN-GNG----------------------------NGNGG-----------GAATASAAAASK 252
            ...|: |:|                            |.||.           .....|.|....
 Worm   322 EVPGSVGHGYAWVPPGLSRKKVEEYMSQLPNNVVPRTNSNGEKLREKQLLLQLPRQDLSVAYCRH 386

  Fly   253 LSADCSGRT-------------EVGHIKCEKNFEL-CEGCGQKIHDRFLM----NVGDA-NWHEQ 298
            |::....:.             ::|::....|..: |..|...:....:.    .:||: .||..
 Worm   387 LTSQTERKVYEEFVNARNEIALDIGYVSSNINKAMECHKCSGILETNEMAVIAPKLGDSTGWHPA 451

  Fly   299 CLACCYCGMQLHHTCY-VRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFV 362
            |..|..|...|....| |:::::||:..|..|...:||:|...|...|..  ...|..:|...|.
 Worm   452 CFTCQACEQLLVDLTYCVKDNQIYCERHYAELHKPRCSACDELIFAGEYT--KAMNKDWHSDHFC 514

  Fly   363 CYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGF-VGLDEEDL------------ 414
            |:.|...| .|:::::||.|.:|.:  ..:::|  |.....|.. :|:|.:||
 Worm   515 CWQCDQTL-TGQRYIMRDEQPYCIK--CYEDVF--ANQCDECAKPIGIDSKDLSYKDKHWHEHCF 574

  Fly   415 ------LRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQ 473
                  :...|...|.|..|...::...:.|....|    .|.::
 Worm   575 LCSMCKISLVDMPFGSKNDRIFCSNCYDQAFATRCD----GCNEI-------------------- 615

  Fly   474 NQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLDS 538
             .||.|||::.|.||                        .:||...|...:|...:..::...|.
 Worm   616 -FRAGMKKMEYKGKQ------------------------WHDKCFCCAHCKLAIGTKSFIPKNDD 655

  Fly   539 TFASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQH 603
            .|..       |...:.:....  |.|...::..|..:.......:.....|.   ::|.:|.:.
 Worm   656 VFCG-------PCYEEKFATRC--SKCKKVITAGGVTYKNEPWHRECFCCTNC---NSSLAGQRF 708

  Fly   604 SHSHSNPH------DMLANLNNSLINPI 625
            :.....|:      |:.|...|:...||
 Worm   709 TSKDEKPYCANCYGDLFAKRCNACTKPI 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	14/57 (25%)
		LIM	333..388	CDD:295319	16/54 (30%)
		Homeobox	427..480	CDD:278475	6/52 (12%)
lim-9	NP_001300395.1	PET_LIMPETin_LIM-9	329..412	CDD:193605	7/82 (9%)
		LIM1_LIMPETin	423..480	CDD:188798	14/56 (25%)
		LIM2_Testin_like	486..541	CDD:188727	16/59 (27%)
		LIM3_LIMPETin	544..602	CDD:188805	11/59 (19%)
		LIM4_LIMPETin	609..662	CDD:188809	17/108 (16%)
		LIM5_LIMPETin	670..721	CDD:188814	7/55 (13%)
		LIM6_LIMPETin	729..784	CDD:188816	3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910