Protein Alignment Lmx1a and ap

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_724428.1
• Gene: ap / 35509
• FlyBaseID: FBgn0267978
• Length: 469
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 132/534 - (24%)
• Similarity: 189/534 - (35%)
• Gaps: 163/534 - (30%)

  Fly    98 HQQQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAA 162
            |.||.|....|......|||    |::...||...:....|||     :.|..||::.:...:..
  Fly    12 HWQQSARFLGPGAREKSPTP----PVAHQGSNQCGSAAGANNN-----HPLFRACSSSSCPDICD 67

  Fly   163 ASAAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNG 227
            .|.      .|.|.:..|........|..|....:||..:...|
  Fly    68 HST------KPFGNAYGTESFRSYETADRATFEDSAAKFSISRS--------------------- 105

  Fly   228 NGNGNGNGNGNGGGAATASAAAASKLSADCSGRTE----------VGHIKCEKNFELCEGCGQKI 282
                           .|.....:.:.::..|.:||          ....|..:|.:.|.|||::|
  Fly   106 ---------------RTDCTEVSDETTSGISFKTEPFGPPSSPESTSDSKITRNLDDCSGCGRQI 155

  Fly   283 HDRFLMNVGDANWHEQCLACCYCGMQLHH--TCYVRNSKLYCKMDYDRLFGV-KCSSCCHAILPQ 344
            .|||.::..:..||..||.|..|...|..  :||.|:..:|||.||...||. :||.|..:|...
  Fly   156 QDRFYLSAVEKRWHASCLQCYACRQPLERESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSN 220

  Fly   345 ELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRH-DLEKEMFLAAAA-------- 400
            ||||| ..|.|||:.||.|..|..||.||:|:.:.|..::|..| .:.:|...|:::
  Fly   221 ELVMR-ARNLVFHVNCFCCTVCHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPYS 284

  Fly   401 -----------------------------AQHCGFVGLDEEDLLRPRDGRRGP------------ 424
                                         |.|. ..||.:....:.|..:|.|
  Fly   285 AQFGSPHNDSSSPHSDPSRSIVPTGIFVPASHV-INGLPQPARQKGRPRKRKPKDIEAFTANIDL 348

  Fly   425 -------------------KRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQV 470
                               ||.||.....|.:..|:.|..:..|..|..:.|::.|||..||:||
  Fly   349 NTEYVDFGRGSHLSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQV 413

  Fly   471 WFQNQRAKMKKIQRKAKQNGGSGGGSGSG---RGTGNSSATDDKDTNDKEDKCVKQELGGDSSGY 532
            ||||.|||.:::..|.         .|||   :|.|    ..|.|:         ..:...:|..
  Fly   414 WFQNARAKWRRMMMKQ---------DGSGLLEKGEG----ALDLDS---------ISVHSPTSFI 456

  Fly   533 LGGLDSTFASQPLN 546
            |||.:||   .|||
  Fly   457 LGGPNST---PPLN 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	22/53 (42%)
		LIM	333..388	CDD:295319	24/54 (44%)
		Homeobox	427..480	CDD:278475	22/52 (42%)
ap	NP_724428.1	LIM1_Lhx2_Lhx9	148..201	CDD:188755	21/52 (40%)
		LIM2_Lhx2_Lhx9	206..264	CDD:188763	25/58 (43%)
		Homeobox	371..424	CDD:395001	22/52 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444990
Domainoid	1	1.000	47	0.796	Domainoid score	I4515
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940