Protein Alignment Lmx1a and HOXC13

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_059106.2
• Gene: HOXC13 / 3229
• HGNCID: 5125
• Length: 330
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 71/352 - (20%)
• Similarity: 107/352 - (30%)
• Gaps: 130/352 - (36%)

  Fly   216 NANGSGNGNGNGNGNGNGNGNGNG-GGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCG 279
            :|..||.|.|.|.|.|...|.|.| .||:...|.:...|.:.|...
Human    22 SAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGLGSSCPAS------------------- 67

  Fly   280 QKIHDRFLM---------------------NVGDANWHEQC-------------------LACCY 304
               |.|.|:                     ::.......||                   ....|
Human    68 ---HCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSY 129

  Fly   305 CGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCH----------AILPQELVMRPIPNFVFHLP 359
            .|.:|.|     |..|..|            .|.:          ..||.:.:......|.|: |
Human   130 YGCRLSH-----NVNLQQK------------PCAYHPGDKYPEPSGALPGDDLSSRAKEFAFY-P 176

  Fly   360 CFVC------------------------YACRLPLQKGEQFMLRDG---QLFCYRHDLEKEMFLA 397
            .|..                        :...:|::..:.:.|.:|   |::|     .||...:
Human   177 SFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYC-----SKEQSQS 236

  Fly   398 AAAAQHCGFVGLDEEDLLRPR--DGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKD 460
            |    |.......:...|:|.  ..|||.|: |...|..|.|:.:..:..|....::.|..::..
Human   237 A----HLWKSPFPDVVPLQPEVSSYRRGRKK-RVPYTKVQLKELEKEYAASKFITKEKRRRISAT 296

  Fly   461 TGLSVRVVQVWFQNQRAKMKKIQRKAK 487
            |.||.|.|.:||||:|.|.||:..|:|
Human   297 TNLSERQVTIWFQNRRVKEKKVVSKSK 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	12/91 (13%)
		LIM	333..388	CDD:295319	12/91 (13%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
HOXC13	NP_059106.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..50		8/19 (42%)
		HoxA13_N	54..166	CDD:315049	18/150 (12%)
		HOX	260..312	CDD:197696	17/52 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910