DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and HOXB7

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_004493.3	Gene:	HOXB7 / 3217	HGNCID:	5118	Length:	217	Species:	Homo sapiens

Alignment Length:	91	Identity:	25/91 - (27%)
Similarity:	42/91 - (46%)	Gaps:	11/91 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   425 KRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQN 489
            ||.|...|..|..:.:..|..:....|:.|..:|....|:.|.:::||||:|.|.|      |:|
Human   138 KRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWK------KEN 196

  Fly   490 GGSGGGSGSGRGTGNSSATDDKDTND 515
            ..:|.|:     ||...|..:::..:
Human   197 KTAGPGT-----TGQDRAEAEEEEEE 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	15/52 (29%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131
		Homeobox	141..193	CDD:278475	15/51 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..217		7/27 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940