DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lmx1a and HOXA7

DIOPT Version :9

Sequence 1:NP_729801.1 Gene:Lmx1a / 39406 FlyBaseID:FBgn0052105 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_008827.2 Gene:HOXA7 / 3204 HGNCID:5108 Length:230 Species:Homo sapiens


Alignment Length:104 Identity:31/104 - (29%)
Similarity:50/104 - (48%) Gaps:6/104 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   423 GP--KRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRK 485
            ||  ||.|...|..|..:.:..|..:....|:.|..:|....|:.|.:::||||:|.|.||   :
Human   127 GPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK---E 188

  Fly   486 AKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQE 524
            .|..|.:...:..| ...:::||...|..|:||...::|
Human   189 HKDEGPTAAAAPEG-AVPSAAATAAADKADEEDDDEEEE 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lmx1aNP_729801.1 LIM1_Lmx1b 275..327 CDD:188757
LIM 333..388 CDD:295319
Homeobox 427..480 CDD:278475 15/52 (29%)
HOXA7NP_008827.2 Antp-type hexapeptide 119..124
Homeobox 134..186 CDD:278475 15/51 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 187..230 11/44 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3844
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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