Protein Alignment Lmx1a and HLX

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 44/205 - (21%)
• Similarity: 75/205 - (36%)
• Gaps: 58/205 - (28%)

  Fly   417 PRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAK--- 478
            |:..:|.....|.:.::.|||..:..|:......:..|:.||...||:...|:|||||:|.|
Human   269 PQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRH 333

  Fly   479 MKKIQRK--------AKQNGGSGGGSGS--------GRGTGNSSATD---------DKDTNDKED 518
            .|:.|.:        .|.:||:....|.        ..|...|.::|         |.:..:..:
Human   334 SKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSE 398

  Fly   519 KCVKQEL------------------GGDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANSNDSFC 565
            :.:.|..                  ||.|.|  ||...:|:          |.....::|..:.|
Human   399 RSLHQTTVIKAPVTGALITASSAGSGGSSGG--GGNSFSFS----------SASSLSSSSTSAGC 451

  Fly   566 SSDLSLDGSN 575
            :|.|...|::
Human   452 ASSLGGGGAS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	18/55 (33%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173
		Abdominal-A	227..>344	CDD:332641	22/74 (30%)
		Homeobox	279..332	CDD:306543	18/52 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		24/143 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910