DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lmx1a and Nkx2-3

DIOPT Version :9

Sequence 1:NP_729801.1 Gene:Lmx1a / 39406 FlyBaseID:FBgn0052105 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_001101064.1 Gene:Nkx2-3 / 309389 RGDID:1308521 Length:362 Species:Rattus norvegicus


Alignment Length:227 Identity:58/227 - (25%)
Similarity:83/227 - (36%) Gaps:66/227 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 LTGQHQQHQQQQHQQQQQH---PHQQH------------------------QQHQQQ------HA 103
            |..|.|..:.::..:||::   |.::|                        :|.|.:      ||
  Rat   151 LFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTHA 215

  Fly   104 ASTTP----VPI-----NSCPTPTGH---SPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLT 156
            ....|    ||:     ..|.||:..   ||....:...::|:......|.|             
  Rat   216 PPPPPRRVAVPVLVRDGKPCVTPSAQAYGSPYGVGAGAYSYNSFPAYGYGNS------------- 267

  Fly   157 AAAVAAASAAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSG 221
            |||.|||:|||.||.:.:|:.......||.     .....||:||||......:|||.|:....|
  Rat   268 AAAAAAAAAAAAAAAAYSGSYGCAYPTGGG-----GGGGGAASAATTAMQPACSATGGGSFVNVG 327

  Fly   222 NGNGNGNGNGNGNGNGNGGGAATASAAAASKL 253
            |..|.|:|   |.......|||..:|.|...|
  Rat   328 NLGGFGSG---GGAQPLHQGAAAGAACAQGTL 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lmx1aNP_729801.1 LIM1_Lmx1b 275..327 CDD:188757
LIM 333..388 CDD:295319
Homeobox 427..480 CDD:278475
Nkx2-3NP_001101064.1 Homeobox 148..202 CDD:395001 7/50 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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