DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lmx1a and dbx1a

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_571233.1	Gene:	dbx1a / 30394	ZFINID:	ZDB-GENE-000128-8	Length:	314	Species:	Danio rerio

Alignment Length:	173	Identity:	43/173 - (24%)
Similarity:	66/173 - (38%)	Gaps:	46/173 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   421 RRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRK 485
            |||..| |.:.:..|||..:..|.:.....:..|:.||...||....|::||||:|.|.:  ..|
Zfish   173 RRGMLR-RAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWR--NSK 234

  Fly   486 AKQNGGSGGGSGSGRGT-----------GNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLDST 539
            .::...|||.......|           |..|:.|:    |::|.|.               .|.
Zfish   235 ERELLSSGGCREQTLPTKTNPHPDLSDVGKKSSEDE----DEDDACA---------------PSH 280

  Fly   540 FASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDD 582
            |.         .||....:||.|    |.::...|:|.:.:|:
Zfish   281 FC---------LSPRRVMSNSTD----SSITFKHSDFSESEDE 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	17/52 (33%)
dbx1a	NP_571233.1	Homeobox	178..231	CDD:278475	18/53 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..279		11/63 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..314		6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910