Protein Alignment Lmx1a and Hoxd13

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001099356.1
• Gene: Hoxd13 / 288154
• RGDID: 1308417
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 410
• Identity: 96/410 - (23%)
• Similarity: 136/410 - (33%)
• Gaps: 135/410 - (32%)

  Fly   119 GHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSP---AGTSVAT 180
            |.:|.|||||.:......     |..|..:.:..::..|||.|||:|||.||.|.   .|||..|
  Rat    12 GAAPASSSSSVAAPGQCR-----GFLSAPVFAGTHSGRAAAAAAAAAAAAAAASSFAYPGTSERT 71

  Fly   181 SQLGGAVAAAIAA----------AAAAAAAATTPTSTGPAATGSGNANGSG-------NGNGNGN 228
            .....:.::|:.|          ..|.|||||.....|..|.|.|...|:|       :|.|...
  Rat    72 GSSSSSSSSAVIATRPEAPVAKECPAPAAAATAAAPPGAPALGYGYHFGNGYYSCRMSHGVGLQQ 136

  Fly   229 GNGNGNGNGNGGGAATASAAAASKLSADCSGRTEV---------------------GHIKCEKNF 272
            .....:.:.:.||.........|.|::......||                     |:|.....|
  Rat   137 NALKSSPHASLGGFPVEKYMDVSGLASSSVPTNEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTF 201

  Fly   273 ELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSC 337
                |.|:..|:.::...|..:|   .||..:            ||::||..|.
  Rat   202 ----GSGEPRHEAYISMEGYQSW---TLANGW------------NSQVYCAKDQ----------- 236

  Fly   338 CHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQ 402
                 ||                            |..|.              |..|
  Rat   237 -----PQ----------------------------GSHFW--------------KSSF------- 247

  Fly   403 HCGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRV 467
             .|.|.|::.|:...|.||    :.|...|..|.|:.:..:..:....:..|..::..|.||.|.
  Rat   248 -PGDVALNQPDMCVYRRGR----KKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQ 307

  Fly   468 VQVWFQNQRAKMKKIQRKAK 487
            |.:||||:|.|.|||..|.|
  Rat   308 VTIWFQNRRVKDKKIVSKLK 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	12/51 (24%)
		LIM	333..388	CDD:295319	4/54 (7%)
		Homeobox	427..480	CDD:278475	16/52 (31%)
Hoxd13	NP_001099356.1	HoxA13_N	<113..162	CDD:289085	9/48 (19%)
		homeodomain	265..321	CDD:238039	17/59 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910