DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and phx1

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_593776.1	Gene:	phx1 / 2542405	PomBaseID:	SPAC32A11.03c	Length:	942	Species:	Schizosaccharomyces pombe

Alignment Length:	232	Identity:	53/232 - (22%)
Similarity:	92/232 - (39%)	Gaps:	27/232 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 PRDG--RRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKM 479
            |..|  ...||..:..||:.|.......|.:...|...:||.:.::..:..|.|.:||||:|||.
pombe   157 PESGGSTSAPKSKKQRLTADQLAYLLREFSKDTNPPPAIREKIGRELNIPERSVTIWFQNRRAKS 221

  Fly   480 KKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDS--SGYLGGL------ 536
            |.|.|:.::.          |........:....|.|..:....|:...|  |.|:||:
pombe   222 KLISRRQEEE----------RQRILREQRELDSLNQKVSQAFAHEVLSTSPTSPYVGGIAANRQY 276

  Fly   537 DSTFASQPLNPNLPFSPDDYPANSNDSFC--SSDL----SLDGSNFDQLDDDADSLSLNNLELQS 595
            .:|...:|......|.....|..|:...|  .||:    ||..:.::.|..:|..:| :..:..:
pombe   277 ANTLLPKPTRKTGNFYMKSGPMQSSMEPCIAESDIPIRQSLSSTYYNSLSPNAVPVS-SQRKYSA 340

  Fly   596 TSSSGNQHSHSHSNPHDMLANLNNSLINPIDKLYLMQ 632
            :|.|...::.|.||....:.:..:|...|:..:.:.|
pombe   341 SSYSAIPNAMSVSNQAFDVESPPSSYATPLTGIRMPQ 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	16/52 (31%)
phx1	NP_593776.1	COG5576	116..272	CDD:227863	32/124 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000