Protein Alignment Lmx1a and Nkx2-4

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_075993.1
• Gene: Nkx2-4 / 228731
• MGIID: 97349
• Length: 354
• Species: Mus musculus
• Alignment Length: 352
• Identity: 82/352 - (23%)
• Similarity: 102/352 - (28%)
• Gaps: 140/352 - (39%)

  Fly   155 LTAAAVAAASAAAVAAPSPAGTSVAT------SQLGGAVAAAIAAAAAAAAAATTPTSTGPAATG 213
            |.|...|||..|..:.||....:||.      :..|...|||.||||||||||.|.......:..
Mouse    38 LGAPLGAAAYRAPPSGPSSQAAAVAAGMQPPHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQF 102

  Fly   214 SGNANGSGNGNGNGN-GNGNGNGNGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEG 277
            ..:|.||....|.|| |......:|..||||   |||.....|:...|
Mouse   103 PHSAMGSYCNGGLGNMGELPAYTDGMRGGAA---AAATGWYGANTDPR----------------- 147

  Fly   278 CGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAIL 342
              .....||:......|         ..||                   ..|.|:.
Mouse   148 --YSSISRFMGPSAGVN---------VAGM-------------------GSLTGIA--------- 173

  Fly   343 PQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFV 407
                                                          |..|.:....|||
Mouse   174 ----------------------------------------------DAAKSLAPLHAAA------ 186

  Fly   408 GLDEEDLLRPRDGRRGPKRPRTILTSQ-QRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVW 471
                            |:|.|.:|.|| |..:.:..|.|........||.||....|:...|::|
Mouse   187 ----------------PRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIW 235

  Fly   472 FQNQRAKMK-----KIQRKAKQNGGSG 493
            |||.|.|||     |..::.:|.||.|
Mouse   236 FQNHRYKMKRQAKDKAAQQLQQEGGLG 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	5/51 (10%)
		LIM	333..388	CDD:295319	0/54 (0%)
		Homeobox	427..480	CDD:278475	19/53 (36%)
Nkx2-4	NP_075993.1	Homeobox	191..244	CDD:278475	19/52 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		5/18 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910