DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and unc-42

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001263845.1	Gene:	unc-42 / 192081	WormBaseID:	WBGene00006778	Length:	279	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	56/218 - (25%)
Similarity:	88/218 - (40%)	Gaps:	51/218 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   414 LLRPRDGR-RGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRA 477
            |.||...| ...:|.||..|.:|.::..|:|.:|..|...|||.||:.|.|:...:||||||:||
Worm    89 LERPESERLNSRRRHRTTFTQEQLQELDAAFQKSHYPDIYVREELARITKLNEARIQVWFQNRRA 153

  Fly   478 KMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLD-STFA 541
            |.:|.:::..:          .....:|..::..:|      .::|.:      |...|: ..|.
Worm   154 KHRKHEKQLNK----------AINPPHSFLSNPANT------LMRQGM------YPAALNRDGFW 196

  Fly   542 SQPLNPNLPFSPDDYPANSN-------------------DSFCSSDLSLDGSNFDQLDDDADSLS 587
            .|.....:|: |...|:.||                   |.|....|:|..:........|.||:
Worm   197 YQSYQRPMPY-PTASPSYSNSFTNPIANFGHSITSFQADDEFYQKSLALRMTTTPSAATAATSLA 260

  Fly   588 LNNLELQSTSSSGNQHSHSHSNP 610
              |:..|.|     |.|.:.:||
Worm   261 --NINYQQT-----QPSEASTNP 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	24/52 (46%)
unc-42	NP_001263845.1	Homeobox	103..157	CDD:365835	24/53 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910