Protein Alignment Lmx1a and Pou3f1

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_035271.1
• Gene: Pou3f1 / 18991
• MGIID: 101896
• Length: 449
• Species: Mus musculus
• Alignment Length: 536
• Identity: 106/536 - (19%)
• Similarity: 162/536 - (30%)
• Gaps: 182/536 - (33%)

  Fly    28 ARFLDNPNPGSMTASSGNSLHLSNSNNNLPTSISGNNSPTATASLTGQHQQHQQQQHQQQQQHPH 92
            |::|.. .||.....:|..:|                ...|.|:.....:.|....:::.|:..|
Mouse     5 AQYLPR-GPGGGAGGTGPLMH----------------PDAAAAAAAAAERLHAGAAYREVQKLMH 52

  Fly    93 QQHQQHQQQHAASTTPVPI---NSCPTPTGHSPLSSSSSNSNHNNNNNNNNG----GSSSNNLHS 150
                 |:...|.:..||.:   ...||..|.....:...:..|........|    |......|
Mouse    53 -----HEWLGAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFH- 111

  Fly   151 ACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGAVAAAIAAAA-------AAAAAATTPTSTG 208
                  |..|...:|.|.||.:..||:   ..||.|::.:..|..       ...|.|..|...|
Mouse   112 ------ARLVHQGAAHAGAAWAQGGTA---HHLGPAMSPSPGAGGGHQPQPLGLYAQAAYPGGGG 167

  Fly   209 PAATGSGNANGSGNGNG-------NGN-------------GNGNGNGNGNGGGAATASAAAASKL 253
            ....|...|.|.|.|.|       :|:             .:|:.:|:.:.||   ..||||...
Mouse   168 GGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGG---LHAAAAHLH 229

  Fly   254 SADCSGRTEVGHIKCE------------KNFELCEGCGQKIHDRFLM-NVGDA------NWHEQC 299
            .....|.:.||....|            |.|:     .::|...|.. :||.|      |...|.
Mouse   230 PGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFK-----QRRIKLGFTQADVGLALGTLYGNVFSQT 289

  Fly   300 LACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCY 364
            ..|.:..:||       :.|..||                        ::|:.|
Mouse   290 TICRFEALQL-------SFKNMCK------------------------LKPLLN----------- 312

  Fly   365 ACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGRRGPKRPRT 429
                      :::...........:|:|      .|||                 ||:  ::.||
Mouse   313 ----------KWLEETDSSSGSPTNLDK------IAAQ-----------------GRK--RKKRT 342

  Fly   430 ILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNG---- 490
            .:....:...::.|.:.|||.......||....|...||:|||.|:|.|.|::...|....
Mouse   343 SIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMD 407

  Fly   491 --------GSGGGSGS 498
                    |.||||.|
Mouse   408 DVYAPGELGPGGGSAS 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	13/58 (22%)
		LIM	333..388	CDD:295319	2/54 (4%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
Pou3f1	NP_035271.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		5/17 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..108		4/31 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..152		4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..251		14/69 (20%)
		POU	245..319	CDD:197673	18/130 (14%)
		Homeobox	340..393	CDD:278475	17/52 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..449		8/31 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030