DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and ceh-37

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001360629.1	Gene:	ceh-37 / 181530	WormBaseID:	WBGene00000458	Length:	292	Species:	Caenorhabditis elegans

Alignment Length:	210	Identity:	54/210 - (25%)
Similarity:	84/210 - (40%)	Gaps:	33/210 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   406 FVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQV 470
            |.|......:.||..|    |.||..:.||.:..:..|:::..|....||.:|....|....:||
Worm    41 FSGAPYNAAMIPRKNR----RERTTYSRQQLEILETLFNETQYPDVFARERVADQIRLQESRIQV 101

  Fly   471 WFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQE-LGGDSSGY-- 532
            ||:|:|||. ::|.|.|..            ..|..:.:.|..:.::...:..| |.|.|.||
Worm   102 WFKNRRAKY-RLQEKQKPK------------RSNEKSQEHKSEDQQQTDVLDGEPLKGGSPGYQP 153

  Fly   533 -----LGGLDSTFASQPLNPNLPFSPDDYPANSNDSFCS-SDLSLDGSN-------FDQLDDDAD 584
                 |...|...||..|......||.:..|::..|..| ::|..:|.:       .:.....|.
Worm   154 QIKSELESCDGAVASGKLGTPKSISPVETTASTTSSNTSAAELQWNGDHKILGFGKNETTTSAAV 218

  Fly   585 SLSLNNLELQSTSSS 599
            |.:.:|....|:|||
Worm   219 SPTADNASTPSSSSS 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319
		Homeobox	427..480	CDD:278475	18/52 (35%)
ceh-37	NP_001360629.1	Homeobox	59..111	CDD:365835	18/52 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910