Protein Alignment Lmx1a and Nkx2-3

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_032725.1
• Gene: Nkx2-3 / 18089
• MGIID: 97348
• Length: 362
• Species: Mus musculus
• Alignment Length: 260
• Identity: 61/260 - (23%)
• Similarity: 85/260 - (32%)
• Gaps: 94/260 - (36%)

  Fly   365 ACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGRRGPKRPRT 429
            ||..|.::.|:.:....|..|   .|:|.:    .||..|    ...||..||:.  |..::||.
Mouse    99 ACSGPKEQEEEVVSERSQKSC---QLKKSL----EAAGDC----KTSEDGERPKP--RSRRKPRV 150

  Fly   430 ILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAK------- 487
            :.:..|..:.:..|.|........||.||....|:...|::||||:|.|.|: ||:.|
Mouse   151 LFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKR-QRQDKSLELGTH 214

  Fly   488 --------------------------QNGGSGGGSGSGR---------GTGNSSA---------- 507
                                      |..||..|.|:|.         |.|||:|
Mouse   215 APPPPPRRVAVPVLVRDGKPCVTPSAQTYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAA 279

  Fly   508 -----------------------TDDKDTNDKEDKCVKQELGGDS---SGYLGGLDSTFASQPLN 546
                                   |....|...:..|  ...||.|   ...|||..|...:|||:
Mouse   280 AAAAYSGSYGCAYPTGGGGGGGGTASAATTAMQPAC--SATGGGSFVNVSNLGGFGSGGGAQPLH 342

  Fly   547  546
            Mouse   343  342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:295319	6/22 (27%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
Nkx2-3	NP_032725.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..149		8/28 (29%)
		HOX	145..201	CDD:197696	17/55 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..222		3/18 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910