Protein Alignment Lmx1a and lim-6

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001256980.1
• Gene: lim-6 / 180459
• WormBaseID: WBGene00002988
• Length: 316
• Species: Caenorhabditis elegans
• Alignment Length: 316
• Identity: 110/316 - (34%)
• Similarity: 171/316 - (54%)
• Gaps: 33/316 - (10%)

  Fly   256 DCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQL--HHTCYVRNS 318
            |.|..|::.........:||.|||..|.||::..|.:.::||.||.|..|.:.|  ...|:.|:.
 Worm    23 DGSTPTDISTTSSTTEDKLCSGCGCLIKDRYIYRVMEDSYHESCLRCSCCQLSLSSFKKCFSRHG 87

  Fly   319 KLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQL 383
            .:||:.|:..|:|.:|..|...:||.::|.| :....:|..||.|.:|:.|...|:::.:.||::
 Worm    88 NIYCEHDHQMLYGKRCRRCMTLLLPTDIVHR-VHFMYYHAQCFSCCSCQRPFNLGDEYHVFDGEV 151

  Fly   384 FCYRHDLEKEMFLAAAAAQHCGFVGLDE-----EDLLRPRDGRRGPKRPRTILTSQQRKQFKASF 443
            || |:|.:          ..|.|..:..     |:::|....|:.||||||||.:|||:|||.:|
 Worm   152 FC-RNDYQ----------SICNFQTISNPDPLMEEVVRSEIHRKTPKRPRTILNAQQRRQFKTAF 205

  Fly   444 DQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSAT 508
            ::|.||.|||||.||.:||||||||||||||||||:||:.:|   :..||.....|.|:...|..
 Worm   206 ERSSKPSRKVREQLANETGLSVRVVQVWFQNQRAKIKKLNKK---DSDSGDTFKHGPGSEGRSTE 267

  Fly   509 DDKDTNDKEDKCVKQELG----GDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANS 560
            |.:.::|:|:..:..:..    .::|.|...:...:       |:..|...:|.:|
 Worm   268 DIRSSDDEEESVINLDADEVETSETSSYTDPIQKLY-------NMTSSQIYFPYHS 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	20/53 (38%)
		LIM	333..388	CDD:295319	17/54 (31%)
		Homeobox	427..480	CDD:278475	40/52 (77%)
lim-6	NP_001256980.1	LIM	42..95	CDD:295319	19/52 (37%)
		LIM	101..157	CDD:295319	18/57 (32%)
		Homeobox	189..242	CDD:278475	40/52 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167146
Domainoid	1	1.000	93	1.000	Domainoid score	I4762
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3240
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001820
OrthoInspector	1	1.000	-	-		otm14531
orthoMCL	1	0.900	-	-		OOG6_105498
Panther	1	1.100	-	-	LDO	PTHR24208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	1	1.000	-	-		X1182
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.820