Protein Alignment Lmx1a and php-3

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_499573.1
• Gene: php-3 / 176640
• WormBaseID: WBGene00004024
• Length: 275
• Species: Caenorhabditis elegans
• Alignment Length: 477
• Identity: 83/477 - (17%)
• Similarity: 131/477 - (27%)
• Gaps: 227/477 - (47%)

  Fly    29 RFLDNPN--PGSMTASSGNSLHLSNSNNNLPTS--ISGNNSPTATASLTGQHQQHQ--QQQHQQQ 87
            :.::|.|  |..:.:|..:..|     :..|||  |..::||..|:|......||.  ..:..|.
 Worm     7 QMMNNSNMPPPFVKSSDSHETH-----DESPTSPFIKRSDSPATTSSAAAAAMQHNFWSTRAAQL 66

  Fly    88 QQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNN-----NNNNNNGGSSSNN 147
            ||                          :.:|.|.:||.||:|..||     .:|::..||.:
 Worm    67 QQ--------------------------SVSGSSGVSSGSSSSASNNLSRTQADNHSERGSDT-- 103

  Fly   148 LHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAAT 212
                          |:|......|:.:|.|:                .|||||...|.:.|...|
 Worm   104 --------------ASSPQVAPLPTSSGMSM----------------PAAAAAGMYPFNAGRFPT 138

  Fly   213 GSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEG 277
                                                                             
 Worm   139 ----------------------------------------------------------------- 138

  Fly   278 CGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAIL 342
                   .|.|.|..:.:::                :..||.......|.              .
 Worm   139 -------EFNMMVNQSMYND----------------FYSNSLAASSWPYS--------------Y 166

  Fly   343 PQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFV 407
            ||:.   |..|:            .:|...|.   |.||..            |...::.|
 Worm   167 PQQY---PFANY------------SMPSLDGN---LNDGGQ------------LEWTSSSH---- 197

  Fly   408 GLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWF 472
                        ..|..::|   .|..|..:.:..|..:....::.|..|||...|:.|.|::||
 Worm   198 ------------AMRKKRKP---YTKAQTLELEKEFLYNTYVSKQKRWELAKYLHLTERQVKIWF 247

  Fly   473 QNQRAKMKKIQRKAKQNGGSGG 494
            ||:|.|.||  :|.:.:|...|
 Worm   248 QNRRMKDKK--QKQRTSGDPTG 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	5/51 (10%)
		LIM	333..388	CDD:295319	9/54 (17%)
		Homeobox	427..480	CDD:278475	17/52 (33%)
php-3	NP_499573.1	Homeobox	202..256	CDD:365835	17/56 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940