DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lmx1a and Y1A5A.1

DIOPT Version :9

Sequence 1:	NP_729801.1	Gene:	Lmx1a / 39406	FlyBaseID:	FBgn0052105	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_497801.1	Gene:	Y1A5A.1 / 175515	WormBaseID:	WBGene00012379	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	125	Identity:	30/125 - (24%)
Similarity:	53/125 - (42%)	Gaps:	9/125 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 TEVGHIKCEK-----NFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKL 320
            |.|.:..|::     :..||..|.|.|....|:.: :..||.....|..|...:..|....::..
Worm    48 TPVFYFNCKRMDRSIDRRLCGHCHQSIGSEALVAM-NRLWHPDHFTCSSCKRPIKQTFQAADNHA 111

  Fly   321 YCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRD 380
            ||...:.:.:..||:.|...::...|:..   :..:|..||.|.:|..||..||.:::.|
Worm   112 YCVQCFAQKYNPKCAGCMETLVDTCLLAL---DRHWHPRCFTCSSCNRPLPNGEFYLVDD 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	12/51 (24%)
		LIM	333..388	CDD:295319	14/48 (29%)
		Homeobox	427..480	CDD:278475
Y1A5A.1	NP_497801.1	LIM	67..117	CDD:295319	12/50 (24%)
Y1A5A.1	NP_497801.1	LIM_DA1	125..176	CDD:188782	13/47 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910