Protein Alignment Lmx1a and DLX6

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 458
• Identity: 88/458 - (19%)
• Similarity: 120/458 - (26%)
• Gaps: 228/458 - (49%)

  Fly    60 ISGNNSPTATASLTGQHQQHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSPLS 124
            :.|.:|..:.....||.||.||||.|||||         |||......|      |.|..||..|
Human    11 LEGQDSSKSAFMEFGQQQQQQQQQQQQQQQ---------QQQQPPPPPP------PPPQPHSQQS 60

  Fly   125 SSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGAVAA 189
            |.:....|          ...:.|||
Human    61 SPAMAGAH----------YPLHCLHS--------------------------------------- 76

  Fly   190 AIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASAAAASKLS 254
               |||||||.:...........||..|:|.||...:                  .|.||...:|
Human    77 ---AAAAAAAGSHHHHHHQHHHHGSPYASGGGNSYNH------------------RSLAAYPYMS 120

  Fly   255 ADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSK 319
                                                     |.|            |:.|:::
Human   121 -----------------------------------------HSQ------------HSPYLQS-- 130

  Fly   320 LYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLF 384
                                                :|
Human   131 ------------------------------------YH--------------------------- 132

  Fly   385 CYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRP--------RDGRRGPK--RPRTILTSQQRKQF 439
                       .::||||..|    |:.|..:.        |...:|.|  :||||.:|.|.:..
Human   133 -----------NSSAAAQTRG----DDTDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQAL 182

  Fly   440 KASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGN 504
            ...|.|:.......|..||...||:...|::||||:|:|.||:.::......|....||...:..
Human   183 NHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPR 247

  Fly   505 SSA 507
            |.|
Human   248 SPA 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	4/51 (8%)
		LIM	333..388	CDD:295319	1/54 (2%)
		Homeobox	427..480	CDD:278475	20/52 (38%)
DLX6	NP_005213.3	COG5576	119..>231	CDD:227863	38/244 (16%)
		Homeobox	170..223	CDD:278475	20/52 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910