Protein Alignment Lmx1a and Lhx2

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_006497796.1
• Gene: Lhx2 / 16870
• MGIID: 96785
• Length: 414
• Species: Mus musculus
• Alignment Length: 418
• Identity: 111/418 - (26%)
• Similarity: 153/418 - (36%)
• Gaps: 130/418 - (31%)

  Fly   274 LCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHH--TCYVRNSKLYCKMDY--------DR 328
            ||.|||.||.||:.:...|..||.:||.||.|.:.|..  ||:.::..:|||.||        .|
Mouse    52 LCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYSPSLHGPHR 116

  Fly   329 LFGV-KCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFC------- 385
            .|.| :|:.|...|...|:||| ..:.|:||.||.|..|...|..|:.|.::|..::|
Mouse   117 RFSVQRCARCHLGISASEMVMR-ARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEAL 180

  Fly   386 --------YRHDLEKEMFLAAAAAQHCGF-------VGL-------------------------- 409
                    :.|........|||||:..|.       :||
Mouse   181 LQGEYPAHFNHADVAAAAAAAAAAKSAGLGSAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADL 245

  Fly   410 ------------DEEDLLR--PRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKD 460
                        |.|.|.|  |....:..||.||.....|.:..|:.|..:..|..|..:.||:.
Mouse   246 AAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQK 310

  Fly   461 TGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQEL 525
            |||:.||:||||||.|||.::                                     ..::||
Mouse   311 TGLTKRVLQVWFQNARAKFRR-------------------------------------NLLRQE- 337

  Fly   526 GGDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNN 590
                   ..|:|.| :...|....|..|....:|::.|..|:..:|         .|..|.:|..
Mouse   338 -------NTGVDKT-SDATLQTGTPSGPASELSNASLSPSSTPTTL---------TDLTSPTLPT 385

  Fly   591 LELQSTSSSGNQHSHS-HSNPHDMLANL 617
            :....||..||...|. ||.....|.||
Mouse   386 VTSVLTSVPGNLEGHEPHSPSQTTLTNL 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	24/61 (39%)
		LIM	333..388	CDD:295319	19/69 (28%)
		Homeobox	427..480	CDD:278475	23/52 (44%)
Lhx2	XP_006497796.1	LIM1_Lhx2	43..106	CDD:188853	23/53 (43%)
		LIM2_Lhx2_Lhx9	119..177	CDD:188763	20/58 (34%)
		COG5576	<255..386	CDD:227863	45/185 (24%)
		Homeobox	278..331	CDD:395001	23/52 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910