Protein Alignment Lmx1a and PRICKLE2

DIOPT Version :9

• Sequence 1: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_011531734.1
• Gene: PRICKLE2 / 166336
• HGNCID: 20340
• Length: 966
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 58/256 - (22%)
• Similarity: 91/256 - (35%)
• Gaps: 47/256 - (18%)

  Fly   259 GRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGD-----------ANWHEQCLACCYCGMQLHHT 312
            ||..|..........:||.||.:|      |.||           ..||..|..|..|...|...
Human   206 GRGNVRPFPVTMTGAICEQCGGQI------NGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDL 264

  Fly   313 CY-VRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQF 376
            .| .::.|:||...:......:|::|...|...|..  ......:|:..|.|:.|...| .|:::
Human   265 IYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECT--EAEGRHWHMKHFCCFECETVL-GGQRY 326

  Fly   377 MLRDGQLFCYRHDLEKEMFLAA----AAAQHCGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRK 437
            ::::|:.:|. |..|.   |.|    ..|||   :|:|:..:  ..||:...........:..:|
Human   327 IMKEGRPYCC-HCFES---LYAEYCDTCAQH---IGIDQGQM--TYDGQHWHATETCFCCAHCKK 382

  Fly   438 QF-------KASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGG 491
            ..       |.......:.|....:....|:..|.      |||.|||..:...|..:|.|
Human   383 SLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSDSA------FQNARAKESRRSAKIGKNKG 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	18/63 (29%)
		LIM	333..388	CDD:295319	12/54 (22%)
		Homeobox	427..480	CDD:278475	11/59 (19%)
PRICKLE2	XP_011531734.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910